产品名称
晒代胱胺 二盐酸盐, powder
SMILES string
NCC[Se][Se]CCN.[H]Cl.[H]Cl
InChI
1S/C4H12N2Se2.ClH/c5-1-3-7-8-4-2-6;/h1-6H2;1H
InChI key
PKRYDZYGNSZBHO-UHFFFAOYSA-N
assay
>98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
yellow to orange
solubility
H2O: soluble, clear to slightly hazy
Quality Level
General description
盐酸硒胱胺有可能阻断甲型和乙型流感病毒相关的 RNA 依赖性 RNA 聚合酶的活性。
Application
硒代胱胺二盐酸盐在体外已被用于测定其对 PP2A 磷酸酶活性的影响。它也被用作二硫键裂解试剂二硫苏糖醇 (DTT) 的催化剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
M S Stewart et al.
Free radical biology & medicine, 26(1-2), 42-48 (1999-01-16)
The cancer chemopreventive effect of selenium cannot be fully accounted for by the role of selenium as a component of the antioxidant enzyme glutathione peroxidase, which suggests that chemoprevention occurs by another mechanism. Several studies have shown that thiol oxidation
Axel L Dessal et al.
Molecular pharmacology, 79(1), 24-33 (2010-10-01)
G protein-coupled receptors transduce signals through heterotrimeric G protein Gα and Gβγ subunits, both of which interact with downstream effectors to regulate cell function. Gβγ signaling has been implicated in the pathophysiology of several diseases, suggesting that Gβγ could be
Megan C Frost et al.
Biomaterials, 26(14), 1685-1693 (2004-12-04)
The current state-of-the-art with respect to the preparation, characterization and biomedical applications of novel nitric oxide (NO) releasing or generating polymeric materials is reviewed. Such materials show exceptional promise as coatings to prepare a new generation of medical devices with
Glutathione peroxidase activity of D,L-seleno-cystine and selenocystamine.
K Yasuda et al.
Biochemical and biophysical research communications, 96(1), 243-249 (1980-09-16)
L Chen et al.
Free radical biology & medicine, 19(6), 713-724 (1995-12-01)
A selenium (Se)-containing immunoconjugate of a human anti-erythrocyte membrane antibody (Ab-Se) has been synthesized via oxidation of the carbohydrate moieties of the antibody and covalent coupling with selenocystamine. The isolated Ab-Se immunoconjugate is shown to be more hemolytic than is
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