RES0197M-A7
MOPS 钠盐
别名:
3-(N-吗啉基)丙磺酸 钠盐, 4-吗啉丙磺酸 钠盐
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关于此项目
经验公式（希尔记法）:
C7H14NNaO4S
化学文摘社编号:
分子量:
231.25
UNSPSC Code:
12161700
NACRES:
NA.21
MDL number:
InChI
1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8;/h1-7H2,(H,9,10,11);/q;+1/p-1
SMILES string
[Na+].[O-]S(=O)(=O)CCCN1CCOCC1
InChI key
MWEMXEWFLIDTSJ-UHFFFAOYSA-M
biological source
synthetic
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin and microbial, tested
useful pH range
6.5-7.9
pKa (25 °C)
7.2
suitability
suitable for manufacturing use
foreign activity
Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
Quality Level
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Application
MOPS Sodium is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS Sodium is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS Sodium is considered to be non-toxic to culture cell lines and provides high solution clarity.
MOPS Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components. MOPSO based buffers have been described for fixation of cells from urine samples.
MOPS Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components. MOPSO based buffers have been described for fixation of cells from urine samples.
General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Packaging
Product is available in the following package sizes:
RES0197M-A701X: 100g container
RES0197M-A702X 1kg container
RES0197M-A704X: 10kg container
RES0197M-A705X: 25kg container
RES0197M-A701X: 100g container
RES0197M-A702X 1kg container
RES0197M-A704X: 10kg container
RES0197M-A705X: 25kg container
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Ying Hou et al.
Biotechnology progress, 31(4), 974-982 (2015-05-29)
Protein A chromatography is widely employed for the capture and purification of monoclonal antibodies (mAbs). Because of the high cost of protein A resins, there is a significant economic driving force to seek new downstream processing strategies. Membrane chromatography has
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