生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
23A8, monoclonal
形式
buffered aqueous solution
分子量
antigen 21 kDa
种属反应性
rat, human, mouse
技术
immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
western blot: 0.5-2.0 μg/mL using rat brain microsomal protein preparation
同位素/亚型
IgG
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ARHGEF6(9459)
mouse ... Arhgef6(73341)
rat ... Arhgef6(363509)
特异性
The antibody recognizes Rac1 with a slight Rac2 cross-reactivity.
免疫原
recombinant protein containing the full length human Rac1.
外形
Solution in 0.1 M Tris-glycine, pH 7.4, containing 0.15 M NaCl and 0.05% sodium azide with 30% glycerol.
制备说明
Purified using protein G
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Laura Barrio-Real et al.
Oncotarget, 9(47), 28612-28624 (2018-07-10)
Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 1 (P-Rex1) is a key mediator of growth factor-induced activation of Rac1, a small GTP-binding protein widely implicated in actin cytoskeleton reorganization. This Guanine nucleotide Exchange Factor (GEF) is overexpressed in human luminal breast cancer
Michael R Dohn et al.
The Journal of cell biology, 184(3), 437-450 (2009-02-04)
p120-catenin regulates epithelial cadherin stability and has been suggested to function as a tumor suppressor. In this study, we used anchorage-independent growth (AIG), a classical in vitro tumorigenicity assay, to examine the role of p120 in a different context, namely
Matthias Rübsam et al.
Nature communications, 8(1), 1250-1250 (2017-11-03)
Generation of a barrier in multi-layered epithelia like the epidermis requires restricted positioning of functional tight junctions (TJ) to the most suprabasal viable layer. This positioning necessitates tissue-level polarization of junctions and the cytoskeleton through unknown mechanisms. Using quantitative whole-mount
Cheng-Wei Lin et al.
Carcinogenesis, 35(11), 2425-2435 (2014-06-28)
Metastatic disease is the leading cause of cancer mortality. Identifying biomarkers and regulatory mechanisms is important toward developing diagnostic and therapeutic tools against metastatic cancer. In this study, we demonstrated that podocalyxin-like 1 (PODXL) is overexpressed in breast tumor cells
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