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Merck
CN

ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

别名:
COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
物种:
UniProtKB ID:
基因ID:
  • Human(9459) Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(73341) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Rat(363509) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Domestic Rabbit(100358647) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • chicken(422247) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • dog(610290) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • domestic cat(101099030) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • domestic guinea pig(100719019) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • naked mole-rat(101700245) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Horse(100056622) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • cow(533823) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • sheep(101104043) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

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Antibodies

货号
说明
物种反应性
应用
Anti-Arhgef6 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-ARHGEF6 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)

proximity ligation assay

western blot
Anti-ARHGEF6, from rabbit, purified by affinity chromatography,
物种反应性
bovine, human, mouse, rat, rhesus macaque
应用
immunocytochemistry
western blot
Anti-ARHGEF6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-Rac antibody produced in mouse, clone 23A8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ARHGEF6,
物种
human
MISSION® esiRNA, targeting mouse Arhgef6,
物种
mouse