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表单
buffered aqueous glycerol solution
比活
~2000 units/mg enzyme protein
分子量
~96 kDa
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... PPP2R4(5524)
生化/生理作用
Protein phosphatase active against phosphorylated Ser/Thr proteins and peptides
单位定义
One unit will release 1.0 nanomole/min of phosphate from a 15 μM solution of active phosphorylase enzyme
外形
Approx. 2 U/microgram in 20 mM MOPS, pH 7.5, 150 mM NaCl, 60 mM 2-mercaptoethanol, 1 mM MgCl2, 2 mM EGTA, 0.1 mM ZnCl2, 0.1 mg/ml BSA, 50% glycerol.
法规信息
新产品
A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation.
A Ito et al.
The EMBO journal, 19(4), 562-571 (2000-02-17)
Both F10 and BL6 sublines of B16 mouse melanoma cells are metastatic after intravenous injection, but only BL6 cells are metastatic after subcutaneous injection. Retrotransposon insertion was found to produce an N-terminally truncated form (Deltagamma1) of the B56gamma1 regulatory subunit
D B DeFranco et al.
Molecular endocrinology (Baltimore, Md.), 5(9), 1215-1228 (1991-09-01)
We have used okadaic acid (OA), a cell-permeable inhibitor of serine/threonine protein phosphatase types 1 (PP-1) and 2A (PP-2A), to demonstrate that the subcellular distribution of glucocorticoid receptor (GR) in rat fibroblasts is influenced by its phosphorylation state. Nuclear GRs
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