推荐产品
检测方案
≥95.0% (HPLC)
质量水平
形式
powder
颜色
white to off-white
mp
225 °C
应用
cell analysis
储存温度
−20°C
SMILES字符串
N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O
InChI
1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1
InChI key
DCWXELXMIBXGTH-QMMMGPOBSA-N
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应用
O-磷酸-L-酪氨酸已用于:
- 作为抗磷酸酪氨酸抗体的稀释剂,研究精子获能
- 在液相色谱-串联质谱(LC-MS-MS)分析中作为氨基酸标准品
- 作为氨基酸标准品在二维薄层电泳系统中分析磷酸化淀粉磷酸化酶(L-SP)上的磷酸化氨基酸
生化/生理作用
磷酸酪氨酸作为蛋白质调控的对接位点,通过刺激酪氨酸磷酸化蛋白与其他蛋白的磷酸酪氨酸结构域相互作用。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Nature methods, 11(5), 585-592 (2014-03-25)
Cell signaling, one of key processes in both normal cellular function and disease, is coordinated by numerous interactions between membrane proteins that change in response to stimuli. We present a split ubiquitin-based method for detection of integral membrane protein-protein interactions
BMC cancer, 16, 35-35 (2016-01-24)
c-Met signaling has been implicated in oncogenesis especially in cells with c-met gene amplification. Since 20 % of gastric cancer patients show high level of c-Met expression, c-Met has been identified as a good candidate for targeted therapy in gastric cancer.
Biology of reproduction, 100(2), 440-454 (2018-09-22)
Mammalian sperm undergo a series of biochemical and physiological changes collectively known as capacitation in order to acquire the ability to fertilize. Although the increase in phosphorylation associated with mouse sperm capacitation is well established, the identity of the proteins
Planta, 223(3), 468-478 (2005-09-10)
A 78-amino acid insertion (L78) is found in the low-affinity type (L-form) of starch phosphorylase (L-SP, EC 2.4.1.1). This insertion blocks the starch-binding site on the L-SP molecule, and it decreases the binding affinity of L-SP toward starch. The computational
PloS one, 11(11), e0166710-e0166710 (2016-11-20)
Grb2-associated binder (Gab) docking proteins regulate signals downstream of a variety of growth factors and receptor tyrosine kinases. Neuregulin-1 (NRG-1), a member of epidermal growth factor family, plays a critical role for cardiomyocyte proliferation and prevention of heart failure via
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