形式
powder
质量水平
mp
235-237 °C (lit.)
SMILES字符串
O=C1C=CC(=O)N1c2ccc3ccc4cccc5ccc2c3c45
InChI
1S/C20H11NO2/c22-17-10-11-18(23)21(17)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)20(14)19(12)13/h1-11H
InChI key
YXKWRQLPBHVBRP-UHFFFAOYSA-N
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应用
用于合成以下化合物的反应物:
作为如下过程的反应物:
- 寡脱氧核苷酸衍生物
- 免疫原性肽的聚合物缀合物
- 用于生物传感应用的修饰寡核苷酸,
作为如下过程的反应物:
- 参与合成热稳定的荧光马来酰亚胺/异丁烯交替共聚物
- 用作衍生剂,用于测定生物样品中谷胱甘肽二硫化物的含量
包装
无底玻璃瓶。内含物在插入的融合锥体内。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
The Journal of biological chemistry, 284(29), 19493-19500 (2009-05-29)
MD-2 is a part of the Toll-like 4 signaling complex with an indispensable role in activation of the lipopolysaccharide (LPS) signaling pathway and thus a suitable target for the therapeutic inhibition of TLR4 signaling. Elucidation of MD-2 structure provides a
Archives of biochemistry and biophysics, 376(2), 313-319 (2000-04-25)
Modification of Escherichia coli phosphofructokinase-2 (Pfk-2) with N-(1-pyrenil)maleimide results in an enzyme form that is inactive. However, the rate of modification is drastically reduced in the presence of the allosteric effector MgATP. The stoichiometry of the label incorporation was found
The Biochemical journal, 376(Pt 1), 277-283 (2003-08-21)
Modification of Escherichia coli phosphofructokinase-2 (Pfk-2) with pyrene maleimide (PM) results in a rapid inactivation of the enzyme. The loss of enzyme activity correlates with the incorporation of 2 mol of PM/mol of subunit and the concomitant dissociation of the
Biochemistry, 45(11), 3534-3541 (2006-03-15)
Human deoxycytidine kinase (dCK) phosphorylates both pyrimidine and purine deoxynucleosides, including numerous nucleoside analogue prodrugs. Energy transfer studies of transfer between Trp residues of dCK and the fluorescent probe N-(1-pyrene)maleimide (PM), which specifically labels Cys residues in proteins, were performed.
Molecular biology reports, 39(9), 8899-8905 (2012-06-19)
Telomerase activity is repressed in normal human somatic cells, but is activated in most cancers, suggesting that telomerase may be an important target for cancer therapy. Agents that interact selectively with telomerase are anticipated to exert specific action on cancer
商品
Self-assembled monolayers (SAMs) have diverse applications; article compares benefits of alkylthiolates on gold SAM systems.
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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