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Merck
CN

P5386

Sigma-Aldrich

Poly-γ-benzyl-L-glutamate

mol wt 70,000-150,000

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别名:
PBLG
CAS号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.26

形式

powder

质量水平

分子量

70,000-150,000

颜色

white to light yellow

储存温度

−20°C

InChI

1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1

InChI key

BGGHCRNCRWQABU-JTQLQIEISA-N

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应用


  • Hydrogen bond formation may enhance RDC-based discrimination of enantiomers.: This research explores the impact of hydrogen bond formation on residual dipolar couplings (RDC) in the discrimination of enantiomers. Poly-y-benzyl-L-glutamate (PBLG) is used as a chiral alignment medium, enhancing the sensitivity and resolution of NMR spectroscopy for enantiomeric analysis (Sager et al., 2024).

  • Potential and performance of anisotropic (19)F NMR for the enantiomeric analysis of fluorinated chiral active pharmaceutical ingredients.: This study highlights the use of PBLG as an alignment medium in anisotropic 19F NMR spectroscopy for analyzing chiral pharmaceutical compounds. The research demonstrates improved enantiomeric discrimination and quantification, crucial for pharmaceutical development (Gouilleux et al., 2024).

  • Block Sequence Effects on the Self-Assembly Behaviors of Polypeptide-Based Penta-Block Copolymer Hydrogels.: This study investigates the self-assembly behavior of block copolymer hydrogels containing PBLG. The research shows how block sequence affects the mechanical properties and potential applications of these hydrogels in biomedical fields (Wang et al., 2024).

  • Liquid crystalline composite hydrogels with large pH-triggered anisotropic swelling for embolotherapy.: This research explores the development of liquid crystalline hydrogels incorporating PBLG for use in embolotherapy. The hydrogels demonstrate significant pH-responsive swelling, making them suitable for targeted medical applications (Zhang et al., 2024).

分析说明

分子量基于粘度。

其他说明

有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Electrospun Poly(γ-Benzyl-l-Glutamate) and Its Alkali-Treated Meshes: Their Water Wettability and Cell-Adhesion Potential.
Hakamada Y, Ohgushi N, et al.
Journal of Biomaterials Science. Polymer Edition, 28(1), 757-765 (2011)
Hua Yu Tian et al.
Biomaterials, 26(20), 4209-4217 (2005-02-03)
A novel amphiphilic biodegradable cationic hyperbranched poly(ethylene glycol)-polyethylenimine-poly(gamma-benzyl L-glutamate) (PEG-PEI-PBLG) block copolymer was successfully synthesized by ring-opening polymerization (ROP) of N-carboxyanhydride of gamma-benzyl-L-glutamate (BLG-NCA) with PEG-PEI as a macroinitiator. PEG-PEI was firstly prepared by coupling of PEG and PEI using
Hiroshi Kuramochi et al.
The journal of physical chemistry. B, 113(46), 15181-15188 (2009-10-28)
An all-atom molecular dynamics simulation of a spherical micelle composed of amphiphilic N-acetylated poly(ethylene glycol)-poly(gamma-benzyl L-glutamate) (PEG-PBLG-Ac) block copolymers was performed in aqueous solution at 298.15 K and 1 atm. Such copolymers have received considerable attention as carriers in drug
Hana Robson Marsden et al.
Biomacromolecules, 11(4), 833-838 (2010-03-25)
Until now, most preparative methods used to form polymeric vesicles involve either organic cosolvents or sonication. In this communication, we demonstrate for the first time a detergent-aided method to produce polymersomes. Peptidic polymersomes were formed from the rod-rod block copolymer
Wenwei Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 26(6), 3929-3941 (2009-12-08)
Surface-initiated vapor deposition polymerization (SI-VDP) is a very effective approach to synthesize grafted poly(amino acids). In this study, we developed an SI-VDP system with pressure and temperature control and demonstrated highly efficient surface-grafting of poly(gamma-benzyl-L-glutamate) (PBLG) on a silicon wafer

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