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Merck
CN
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文件

P4663

Sigma-Aldrich

聚L -精氨酸 盐酸盐

mol wt 5,000-15,000

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别名:
L-Arginine homopolymer hydrochloride
CAS号:
26982-20-7
MDL编号:
MFCD00166393
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
24898490
NACRES:
NA.26

形式

powder

质量水平

200

分子量

5,000-15,000

颜色

white to off-white

应用

cell analysis
detection

储存温度

−20°C

SMILES字符串

Cl.NC(CCCNC(N)=N)C(O)=O

InChI

1S/C18H38N12O4.ClH/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25;/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28);1H/t10-,11-,12-;/m0./s1

InChI key

PQEISBBDIRAKGR-LFELFHSZSA-N

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相关类别

应用


  • Interfacial Electrostatics of Poly(vinylamine hydrochloride), Poly(diallyldimethylammonium chloride), Poly-L-lysine, and Poly-L-arginine Interacting with Lipid Bilayers.: This research investigates the interactions between poly-L-arginine hydrochloride and lipid bilayers, providing insights into its potential applications in drug delivery systems (McGeachy et al., 2018). (McGeachy et al., 2018).

质量

含有3%或更低的鸟氨酸残基。

分析说明

分子量基于前体聚-L-鸟氨酸的粘度。

其他说明

有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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M Miyamoto et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 52(1), 21-30 (2001-07-05)
The effects of the concentration and molecular weight of poly-L-arginine (poly-L-Arg) on the in vivo nasal absorption of fluorescein isothiocyanate-labeled dextran (MW, 4 kDa, FD-4) in rats were studied. When poly-L-Arg with a range of different molecular weights (MW, 8.9
Keerthi Nadimidla et al.
Biopolymers, 107(9) (2017-05-01)
Tau protein plays a major role in Alzheimer's disease. The tau protein loses its functionality by self-aggregation due to the two six-amino acid sequences VQIVYK and VQIINK of the protein. Hence it is imperative to find therapeutics that could inhibit
Analysis of transient and reversible effects of poly-L-arginine on the in vivo nasal absorption of FITC-dextran in rats.
Ohtake K, Natsume H, Ueda H, et al.
J. Controlled Release, 82, 263-275 (2002)
Ramsha Aamir et al.
International journal of molecular sciences, 22(21) (2021-11-14)
Ischemic stroke is the most common type of stroke and thrombolytic therapy is the only approved treatment. However, current thrombolytic therapy with tissue plasminogen activator (tPA) is often hampered by the increased risk of hemorrhage. Plasmin, a direct fibrinolytic, has
Poly-L-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium.
Ohtake K, Maeno T, Ueda H, et al.
Pharmaceut. Res., 20, 1838-1845 (2003)
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