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产品线
BioReagent
质量水平
方案
≥98%
表单
powder
分子量
Mw 247.14 g/mol
技术
cell culture | mammalian: suitable
颜色
off-white to yellow-brown
mp
140-143 °C
溶解性
1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green
储存温度
−20°C
SMILES字符串
CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O
InChI
1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChI key
NGVDGCNFYWLIFO-UHFFFAOYSA-N
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一般描述
磷酸吡哆醛(PLP,Pyridoxal-5'-磷酸盐,P5P)是一些酶的辅基。它是维生素 B6 的活性形式,由吡哆醛、吡哆胺和吡哆醇三种天然有机化合物组成。PLP 在所有的转氨反应中,以及在一些氨基酸的脱羧和脱氨反应中都起辅酶的作用。
应用
- 血液透析膜的分层表面结构,基于5′-磷酸吡哆醛的多功能作用去除同型半胱氨酸。:讨论了使用吡哆醛5′-磷酸的先进血液透析膜的发展,强调了其在降低同型半胱氨酸水平方面的作用,可能有助于改善透析患者的预后(Jiang P et al., 2020)。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Bioorganic & medicinal chemistry, 18(7), 2412-2427 (2010-03-26)
Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of
Biology open, 4(8), 1052-1061 (2015-07-15)
Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic PCM assembly, but the Drosophila Pericentrin-like protein (PLP) appears to have a more minor role in
The Journal of general virology, 96(Pt 2), 294-310 (2014-10-30)
Chikungunya virus (CHIKV) has recently affected millions of people in the Indian Ocean, with rare cases of encephalopathy and encephalitis occurring in neonates. In the study described herein, the capacity of mouse brain cells to control infection through innate immune
Neurology, 84(2), 148-158 (2014-12-17)
To assess, in a surgical biopsy cohort of active demyelinating lesions, the diagnostic utility of aquaporin-4 (AQP4) immunohistochemistry in identifying neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD) and describe pathologic features that should prompt AQP4 immunohistochemical analysis and AQP4-immunoglobulin
Cell, 180(6), 1178-1197 (2020-03-24)
Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it remains unknown whether mitochondrial disruption contributes to social behavioral deficits. Here, we show that Drosophila mutants in the homolog of
商品
Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.
该页面针对维生素B6、吡哆醛和吡哆醇如何影响无血清、无蛋白细胞培养系统(用于包括单克隆抗体在内的异源蛋白的生物制造)的性能提供了全面的分析。本页介绍吡哆醛、吡哆醇的体外化学和生物化学。
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