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Merck
CN
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文件

P3657

Sigma-Aldrich

吡哆醛5'-磷酸盐 水合物

powder, BioReagent, suitable for cell culture

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别名:
3-羟基-2-甲基-5-([磷酰氧基]甲基）-4-吡啶甲醛, PLP, 吡哆醛5-磷酸, 辅脱羧酶
经验公式（希尔记法）:
C8H10NO6P · xH2O
CAS号:
853645-22-4
分子量:
247.14 (anhydrous basis)
Beilstein:
234749
EC 号:
200-208-3
MDL编号:
MFCD00006333
UNSPSC代码:
12352205
PubChem化学物质编号:
24898438
NACRES:
NA.75

产品线

BioReagent

质量水平

200

检测方案

≥98%

形式

powder

分子量

Mw 247.14 g/mol

技术

cell culture | mammalian: suitable

颜色

off-white to yellow-brown

mp

140-143 °C

溶解性

1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green

储存温度

−20°C

SMILES字符串

CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O

InChI

1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

InChI key

NGVDGCNFYWLIFO-UHFFFAOYSA-N

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相关类别

一般描述

磷酸吡哆醛（PLP，Pyridoxal-5'-磷酸盐，P5P）是一些酶的辅基。它是维生素 B6 的活性形式，由吡哆醛、吡哆胺和吡哆醇三种天然有机化合物组成。PLP 在所有的转氨反应中，以及在一些氨基酸的脱羧和脱氨反应中都起辅酶的作用。

应用


  • Hierarchical Surface Architecture of Hemodialysis Membranes for Eliminating Homocysteine Based on the Multifunctional Role of Pyridoxal 5′-phosphate.: Discusses the development of advanced hemodialysis membranes using pyridoxal 5′-phosphate, highlighting its role in reducing homocysteine levels, which could contribute to improved outcomes for dialysis patients (Jiang P et al., 2020).

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Ivone Carvalho et al.
Bioorganic & medicinal chemistry, 18(7), 2412-2427 (2010-03-26)
Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of
Trina Das et al.
The Journal of general virology, 96(Pt 2), 294-310 (2014-10-30)
Chikungunya virus (CHIKV) has recently affected millions of people in the Indian Ocean, with rare cases of encephalopathy and encephalitis occurring in neonates. In the study described herein, the capacity of mouse brain cells to control infection through innate immune
Jennifer H Richens et al.
Biology open, 4(8), 1052-1061 (2015-07-15)
Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic PCM assembly, but the Drosophila Pericentrin-like protein (PLP) appears to have a more minor role in
Bogdan F G Popescu et al.
Neurology, 84(2), 148-158 (2014-12-17)
To assess, in a surgical biopsy cohort of active demyelinating lesions, the diagnostic utility of aquaporin-4 (AQP4) immunohistochemistry in identifying neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD) and describe pathologic features that should prompt AQP4 immunohistochemical analysis and AQP4-immunoglobulin
Jun Araki et al.
Transplantation, 99(4), 687-692 (2015-01-22)
For managing major limb amputation, it is important to consider ischemic time and reperfusion injury by free radicals after the blood supply is reestablished. State of preservation during transplant surgery is crucial for the survival and function of the tissue
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