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Merck
CN

P3032

青霉素G 钠盐

powder, suitable for cell culture, BioReagent

别名:

苄青霉素 钠盐

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关于此项目

经验公式（希尔记法）:
C16H17N2NaO4S
化学文摘社编号:
69-57-8
分子量:
356.37
NACRES:
NA.76
PubChem Substance ID:
24898384
eCl@ss:
34010400
UNSPSC Code:
12352207
EC Number:
200-710-2
MDL number:
MFCD00069666
Beilstein/REAXYS Number:
3834217

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产品名称

青霉素G 钠盐, powder, BioReagent, suitable for cell culture

InChI key

FCPVYOBCFFNJFS-LQDWTQKMSA-M

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

SMILES string

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

product line

BioReagent

form

powder

potency

≥1477 units per mg

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 100 mg/mL

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

Quality Level

200

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Application

青霉素 G 是一种窄谱天然抗生素。它可有效对抗肺炎链球菌、A、B、C 和 G 组链球菌、非肠球菌 D 组链球菌、草绿色组链球菌和不产生青霉素酶的葡萄球菌。它已用于研究耐庆大霉素粪肠球菌序列 6 型（青霉素敏感性降低）以及在细胞培养中单独使用以及与链霉素和其它抗生素联用的诊断和治疗意义。

Biochem/physiol Actions

作用机制：青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联，从而抑制细胞壁合成。

抗菌谱：本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

Disclaimer

溶液应过滤除菌，2-8℃可储存1周，-20°C可保存更长时间。 溶液在 37°C 下可稳定保存 3 天。 钠盐形式可以100 mg/mL溶于水。

General description

化学结构:β-内酰胺
溶液应过滤除菌，2-8℃可储存1周，-20℃可保存更长时间。 溶液在 37°C 下可稳定保存 3 天。

Other Notes

1mu,10mu,25mu,100mu
将容器密闭保存在干燥和通风良好的地方。产品含青霉素。在干燥处保存。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number
0000480612
0000480611
0000480611
0000480612
0000457907

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商品

Inhibition of Cell Wall Biosynthesis by Antibiotics

β-lactam antibacterials inhibit transpeptidase enzymes, preventing peptidoglycan assembly in both Gram-positive and Gram-negative bacteria.

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