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Merck
CN

P3032

Sigma-Aldrich

青霉素G 钠盐

powder, suitable for cell culture, BioReagent

别名:

苄青霉素 钠盐

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About This Item

经验公式(希尔记法):
C16H17N2NaO4S
CAS号:
分子量:
356.37
Beilstein:
3834217
EC 号:
MDL编号:
UNSPSC代码:
12352207
eCl@ss:
34010400
PubChem化学物质编号:
NACRES:
NA.76

product name

青霉素G 钠盐, powder, BioReagent, suitable for cell culture

产品线

BioReagent

质量水平

形式

powder

效能

≥1477 units per mg

技术

cell culture | mammalian: suitable

溶解性

H2O: 100 mg/mL

抗生素抗菌谱

Gram-positive bacteria

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES字符串

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

FCPVYOBCFFNJFS-LQDWTQKMSA-M

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相关类别

一般描述

化学结构:β-内酰胺
Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days.

应用

青霉素 G 是一种窄谱天然抗生素。它可有效对抗肺炎链球菌、A、B、C 和 G 组链球菌、非肠球菌 D 组链球菌、草绿色组链球菌和不产生青霉素酶的葡萄球菌。它已用于研究耐庆大霉素粪肠球菌序列 6 型(青霉素敏感性降低)以及在细胞培养中单独使用以及与链霉素和其它抗生素联用的诊断和治疗意义。

生化/生理作用

作用机制:青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联,从而抑制细胞壁合成。

抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

注意

溶液应过滤除菌,2-8℃可储存1周,-20°C可保存更长时间。 溶液在 37°C 下可稳定保存 3 天。 钠盐形式可以100 mg/mL溶于水。

其他说明

1mu,10mu,25mu,100mu
将容器密闭保存在干燥和通风良好的地方。产品含青霉素。在干燥处保存。

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WGK 3

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