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关于此项目
经验公式（希尔记法）:
C42H80NO4Cl
化学文摘社编号:
分子量:
698.54
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g ((890890P-1G)), pkg of 2 × 100 mg ((890890P-200MG)), pkg of 5 × 100 mg ((890890P-100MG)), pkg of 1 × 25 mg ((890890P-25MG))
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
advanced drug delivery
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]
InChI
1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
InChI key
KSXTUUUQYQYKCR-LQDDAWAPSA-M
Application
18:1 TAP (DOTAP)可用于在氯仿溶液中形成干膜，制备阳离子脂质体。也用于标准储备溶液中，制备阳离子脂质体。
Biochem/physiol Actions
DOTAP（1,2-二油酰基-3-三甲基铵-丙烷）为阳离子脂质结构，用于体内和体外核酸和蛋白递送。脂质组成和细胞类型会影响 DOTAP 的转染潜能。DOTAP介导造血干细胞(HSCs)的基因敲低技术。
Packaging
5 mL透明玻璃密封安瓿瓶(890890P-200mg)
5 mL透明玻璃密封安瓿瓶(890890P-25mg)
5 mL透明玻璃密封安瓿瓶(890890P-500mg)
60 mL琥珀色宽口螺帽玻璃瓶(890890P-1g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysis of cationic liposomes by reversed-phase HPLC with evaporative light-scattering detection
Zhong Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 51(4), 947-951 (2010)
Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis
Li Y, et al.
BMC Pharmacology & Toxicology, 19(1), 43-43 (2018)
Efficient siRNA delivery by the cationic liposome DOTAP in human hematopoietic stem cells differentiating into dendritic cells
Martino S, et al.
BioMed Research International, 2009 (2009)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 890890P-500MG | 04061835188543 |
| 890890P-25MG | 04061835188536 |
| 890890P-200MG | 04061835188529 |
| 890890P-1G | 04061835188512 |