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Merck
CN
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文件

P2658

Sigma-Aldrich

聚-L-赖氨酸 盐酸盐

suitable for cell culture, Mol wt 15,000-30,000

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别名:
L-Lysine hydrochloride homopolymer
CAS号:
26124-78-7
MDL编号:
MFCD00081870
UNSPSC代码:
12352209
eCl@ss:
32160406
NACRES:
NA.26

形式

powder or solid

质量水平

200

分子量

15,000-30,000

技术

cell culture | mammalian: suitable

颜色

white to light yellow

应用

cell analysis

储存温度

−20°C

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应用

聚赖氨酸盐酸盐已被用于涂覆载玻片和盖玻片，以促进细胞附着。
分子量 >70,000 的聚赖氨酸适用于促进细胞粘附到固体基质。

生化/生理作用

一般认为赖氨酸可以预防骨质疏松症，骨质疏松症是血管钙化的一个特征。戊二酸尿症ⅰ型和吡哆醇依赖性癫痫的发生是由于缺乏赖氨酸分解代谢途径。赖氨酸参与一氧化氮合成的调节。它具有抗病毒活性，因此用于治疗单纯疱疹。赖氨酸与许多生化反应有关，如乙酰化、O-连接的糖基化、泛素化和蛋白质甲基化。一般认为聚赖氨酸是一种生物相容性聚合物，用于跨细胞膜给药。它可用作磁共振成像中的纳米造影剂之一。

分析说明

分子量基于粘度。

其他说明

有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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The role of signaling pathways on proliferation and self-renewal of cultured bovine primitive germ cells
Sahare Mahesh
Reproductive medicine and biology, 14(1) (2015)
Multi-technique characterization of poly-L-lysine dendrigrafts-Cu(II) complexes for biocatalysis.
Rossi JC
Macromolecular Bioscience, 15(2), 275-290 (2015)
Archishman Ghosh et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(39), 19474-19483 (2019-09-12)
Membraneless organelles, corresponding to the droplet phase upon liquid-liquid phase separation (LLPS) of protein or protein-RNA mixtures, mediate myriad cellular functions. Cells use a variety of biochemical signals such as expression level and posttranslational modification to regulate droplet formation and
Mahesh Sahare et al.
Reproduction, fertility, and development, 28(12), 2039-2050 (2015-07-17)
Spermatogonial stem cells (SSCs) are unipotent in nature, but mouse SSCs acquire pluripotency under the appropriate culture conditions. Although culture systems are available for rodent and human germ-cell lines, no proven culture system is yet available for livestock species. Here
Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I.
Posset R
Journal of inherited metabolic disease, 38(2), 265-272 (2015)
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