product name
-吡哌酸, 99% (titration)
质量水平
检测方案
99% (titration)
形式
powder
技术
GC/MS: suitable
颜色
white
mp
272 °C (lit.)
SMILES字符串
OC(=O)[C@@H]1CCCCN1
InChI
1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1
InChI key
HXEACLLIILLPRG-YFKPBYRVSA-N
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一般描述
L-哌啶酸(哌啶-2-羧酸)是含氮的杂环化合物。它属于亚氨基酸。分子量为129.2。
应用
L-哌啶酸已用作气相色谱-质谱分析(GC-MS)中的定量标准品。
生化/生理作用
L-哌啶酸可用于泽尔韦格氏综合征。哌啶酸也是一种植物防御代谢物。它是一种信号传导化合物,对系统获得抗性(SAR)至关重要。
L-哌啶酸是赖氨酸代谢物;其分解代谢缺陷与高磷血症、脑肝肾综合征、新生儿肾上腺脑白质营养不良和婴儿雷夫森病有关。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Pipecolic acid
Laboratory Guide to the Methods in Biochemical Genetics (2008)
Transcriptional analysis of defense mechanisms in upland tetraploid switchgrass to greenbugs
BMC plant biology, 17(1), 46-46 (2017)
The Journal of biological chemistry, 264(5), 2509-2517 (1989-02-15)
L-Pipecolic acid oxidation was studied in the rabbit and cynomolgus monkey. Tissue homogenates from both species incubated with L-[2,3,4,5,6-3H]pipecolic acid produced a single radioactive product identified as alpha-aminoadipic acid. In the rabbit, L-pipecolic acid oxidation was greatest in kidney cortex
Annals of neurology, 47(1), 109-113 (2000-01-13)
We describe an 18-year-old patient with psychomotor retardation and abnormally short metatarsi and metacarpals but no other signs of classic Refsum disease. Molecular analysis of the phytanoyl-coenzyme A hydroxylase gene revealed a homozygous deletion causing a frameshift. Surprisingly, L-pipecolic acid
Pediatric research, 25(5), 548-552 (1989-05-01)
L-Pipecolic acid, a cyclic imino acid produced during the degradation of lysine, accumulates in body fluids of infants with the generalized peroxisomal disorders, including Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease. Peroxisome-enriched fractions from normal human liver oxidized L-[3H]pipecolic
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