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Merck
CN

P0275

多聚谷氨酸酪氨酸 钠盐

greener alternative

Glu:Tyr (4:1), mol wt 20,000-50,000

别名:

L-Glutamic acid sodium salt (1:1) polymer with L-tyrosine

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关于此项目

化学文摘社编号:
97105-00-5
UNSPSC Code:
12352209
NACRES:
NA.26
MDL number:
MFCD00148022

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产品名称

多聚谷氨酸酪氨酸 钠盐, Glu:Tyr (4:1), mol wt 20,000-50,000

form

powder

feed ratio

Glu:Tyr (4:1)

mol wt

20,000-50,000

greener alternative product score

old score: 48
new score: 45
Find out more about DOZN™ Scoring

greener alternative product characteristics

Safer Solvents and Auxiliaries
Design for Energy Efficiency
Reduce Derivatives
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

color

white to off-white

greener alternative category

, Re-engineered

storage temp.

−20°C

Quality Level

200

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相关类别

Analysis Note

分子量基于粘度。也由MALLS测定。

Application

聚谷氨酸酪氨酸钠盐可作为底物用于
  • Janus激酶3(JAK3)的基于酶联免疫吸附分析(ELISA)的检测
  • 原癌基因酪氨酸蛋白激酶(Src)和T细胞受体ζ链关联蛋白激酶(Zap70)
  • 体外酪氨酸酶检测

Biochem/physiol Actions

聚（谷氨酸，酪氨酸）钠盐是一种多聚氨基酸，可用于癌症研究。

General description

我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别，在“更安全的溶剂和助剂”、“节能设计”和“减少衍生品”绿色化学原理方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

Other Notes

有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000357375
0000357376
0000357377
0000361810
0000361811

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A simple and robust automated kinase profiling platform using luminescent ADP accumulation technology
Larson B, et al.
Assay and Drug Development Technologies, 7(6), 573-584 (2009)
Identification of Chinese Herbal Compounds with Potential as JAK3 Inhibitors
Su D, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM (2019)
Dimerization of the Pragmin pseudo-kinase regulates protein tyrosine phosphorylation
Lecointre C, et al.
Structure, 26(4), 545-554 (2018)
Jiaye Guo et al.
Biochemistry, 57(32), 4934-4951 (2018-07-06)
Human epidermal growth factor receptor 2 (HER2) is a validated breast cancer drug target for small molecule inhibitors that target the ATP-binding pocket of the kinase domain. In this work, a large-scale virtual screen was performed to a novel homology
C J Bruns et al.
Cancer research, 60(11), 2926-2935 (2000-06-13)
We determined whether down-regulation of the epidermal growth factor-receptor (EGF-R) signaling pathway by oral administration of a novel EGF-R tyrosine kinase inhibitor (PKI166) alone or in combination with gemcitabine (administered i.p.) can inhibit growth and metastasis of human pancreatic carcinoma
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商品

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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