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Merck
CN

P0275

Sigma-Aldrich

多聚谷氨酸酪氨酸 钠盐

greener alternative

Glu:Tyr (4:1), mol wt 20,000-50,000

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别名:
L-Glutamic acid sodium salt (1:1) polymer with L-tyrosine
CAS号:
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.26

形式

powder

质量水平

投料比

Glu:Tyr (4:1)

分子量

20,000-50,000

环保替代产品得分

old score: 48
new score: 45
Find out more about DOZN™ Scoring

环保替代产品特性

Safer Solvents and Auxiliaries
Design for Energy Efficiency
Reduce Derivatives
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

颜色

white to off-white

环保替代产品分类

储存温度

−20°C

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我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别,在“更安全的溶剂和助剂”、“节能设计”和“减少衍生品”绿色化学原理方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

应用

聚谷氨酸酪氨酸钠盐可作为底物用于
  • Janus激酶3(JAK3)的基于酶联免疫吸附分析(ELISA)的检测
  • 原癌基因酪氨酸蛋白激酶(Src)和T细胞受体ζ链关联蛋白激酶(Zap70)
  • 体外酪氨酸酶检测

生化/生理作用

聚(谷氨酸,酪氨酸)钠盐是一种多聚氨基酸,可用于癌症研究。

分析说明

分子量基于粘度。也由MALLS测定。

其他说明

有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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A simple and robust automated kinase profiling platform using luminescent ADP accumulation technology
Larson B, et al.
Assay and Drug Development Technologies, 7(6), 573-584 (2009)
Identification of Chinese Herbal Compounds with Potential as JAK3 Inhibitors
Su D, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM (2019)
Dimerization of the Pragmin pseudo-kinase regulates protein tyrosine phosphorylation
Lecointre C, et al.
Structure, 26(4), 545-554 (2018)
C J Bruns et al.
Cancer research, 60(11), 2926-2935 (2000-06-13)
We determined whether down-regulation of the epidermal growth factor-receptor (EGF-R) signaling pathway by oral administration of a novel EGF-R tyrosine kinase inhibitor (PKI166) alone or in combination with gemcitabine (administered i.p.) can inhibit growth and metastasis of human pancreatic carcinoma
Jiaye Guo et al.
Biochemistry, 57(32), 4934-4951 (2018-07-06)
Human epidermal growth factor receptor 2 (HER2) is a validated breast cancer drug target for small molecule inhibitors that target the ATP-binding pocket of the kinase domain. In this work, a large-scale virtual screen was performed to a novel homology

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