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Merck
CN

O9504

Sigma-Aldrich

草酰乙酸

powder, suitable for hybridoma

别名:

2-氧代丁二酸, 丁酮二酸, 氧代丁二酸, 草醋酸

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About This Item

线性分子式:
HOOCCH2COCOOH
CAS号:
分子量:
132.07
Beilstein:
1705475
EC 号:
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.75

检测方案

≥97% (HPLC)

质量水平

形式

powder

技术

cell culture | hybridoma: suitable

杂质

endotoxin, tested

溶解性

H2O: 100 mg/mL

储存温度

−20°C

SMILES字符串

OC(=O)CC(=O)C(O)=O

InChI

1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)

InChI key

KHPXUQMNIQBQEV-UHFFFAOYSA-N

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应用

在杂交瘤细胞培养应用中用作 TCA(Krebs 循环)中间体补充剂。增强杂交瘤生长和生产力。

法律信息

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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It is well established that glutamate acts as an important mediator of neuronal degeneration during cerebral ischemia. Different kind of glutamate antagonists have been used to reduce the deleterious effects of glutamate. However, their preclinical success failed to translate into
E Esenmo et al.
The American journal of physiology, 263(1 Pt 1), E36-E41 (1992-07-01)
Estimating the rate of hepatic gluconeogenesis in vivo from the incorporation of 14C from 14CO2 into glucose requires determination of the rates in liver of equilibration of oxaloacetate with fumarate, conversion of oxaloacetate to phosphoenolpyruvate (PEP), and conversion of PEP
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Glia, 60(1), 147-158 (2011-11-05)
Pyruvate carboxylation (PC) is thought to be the major anaplerotic reaction for the tricarboxylic acid cycle and is necessary for de novo synthesis of amino acid neurotransmitters. In the brain, the main enzyme involved is pyruvate carboxylase, which is predominantly
E Dworzak et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 23(6), 323-329 (1985-06-01)
Evidence is presented for defective pyruvate dehydrogenase (EC 4.1.1.1) in leukocytes and muscle tissue from a 10-year old child with persistent lactic acidosis, suffering from myasthenia and growth retardation. The defect is expressed in vitro by a depressed stimulation of
Anthony Gandin et al.
Plant & cell physiology, 53(9), 1627-1637 (2012-08-01)
In higher plants, the mitochondrial electron transport chain has non-phosphorylating alternative pathways that include the alternative terminal oxidase (AOX). This alternative pathway has been suggested to act as a sink for dissipating excess reducing power, minimizing oxidative stress and possibly

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