所有图片(2)
别名:
(R)-2,5-二氨基戊酸 单盐酸盐
经验公式（希尔记法）:
C5H12N2O2 · HCl
CAS号:
分子量:
168.62
Beilstein:
4153339
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
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检测方案
~98%
质量水平
形式
powder
颜色
white
mp
239 °C
SMILES字符串
Cl[H].NCCC[C@@H](N)C(O)=O
InChI
1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m1./s1
InChI key
GGTYBZJRPHEQDG-PGMHMLKASA-N
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生化/生理作用
D-鸟氨酸在半胱氨酸残基处裂解蛋白质。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Susan E Cellitti et al.
Nature chemical biology, 7(8), 528-530 (2011-04-29)
D-ornithine has previously been suggested to enhance the expression of pyrrolysine-containing proteins. We unexpectedly discovered that uptake of D-ornithine results in the insertion of a new amino acid, pyrroline-carboxy-lysine (Pcl) instead of the anticipated pyrrolysine (Pyl). Our feeding and biochemical
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
Irene Tsiapa et al.
Nuclear medicine and biology, 40(2), 262-272 (2012-12-15)
Radiolabeled RGD peptides that specifically target integrin α(ν)β(3) have great potential in early tumor detection through noninvasive monitoring of tumor angiogenesis. Based on previous findings of our group on radiopeptides containing positively charged aminoacids, we developed a new cyclic cRGDfK
D Amelio et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 164(2), 356-362 (2012-11-06)
The Frank-Starling law is a fundamental property of the vertebrate myocardium which allows, when the end-diastolic volume increases, that the consequent stretch of the myocardial fibers generates a more forceful contraction. It has been shown that in the eel (Anguilla
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