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Merck
CN

O4386

L -鸟氨酸 单盐酸盐

≥99%, BioXtra

别名:

(S)-2,5-二氨基戊酸 单盐酸盐

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关于此项目

经验公式(希尔记法):
C5H12N2O2 · HCl
化学文摘社编号:
分子量:
168.62
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
221-678-6
MDL number:
Beilstein/REAXYS Number:
3625847
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产品名称

L -鸟氨酸 单盐酸盐, BioXtra, ≥99%

product line

BioXtra

Quality Level

assay

≥99%

form

powder

impurities

ammonia- and citrulline-free, essentially free, ≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white

solubility

H2O: 1 M at 20 °C, clear, faintly yellow

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

Cl.NCCC[C@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1

InChI key

GGTYBZJRPHEQDG-WCCKRBBISA-N

Biochem/physiol Actions

L-Ornithine is a not encoded by DNA. It is a free amino acid but do not participate in the protein synthesis. It is formed by the action of the enzyme arginase on L-arginine in the process of forming urea. It is implicated in the reduction of blood ammonia level and improves the efficiency of energy production to cause ammonia detoxification. L-ornithine promotes the release of growth hormone by triggering the pituitary gland.

Other Notes

精氨酸通过精氨酸酶降解所得产物


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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The effect of L-ornithine hydrochloride ingestion on performance during incremental exhaustive ergometer bicycle exercise and ammonia metabolism during and after exercise
Demura S, et al.
European Journal of Clinical Nutrition, 64(10), 1166-1171 (2010)
L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism
Sugino T, et al.
Nutrition Research (New York, N.Y.), 28(11), 738-743 (2008)
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming



全球贸易项目编号

货号GTIN
O4386-25G04061833612415
O4386-100G04061833612408