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线性分子式:
CH3(CH2)3CH(NH2)CO2H
化学文摘社编号:
分子量:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
206-321-4
MDL number:
Beilstein/REAXYS Number:
1721750
产品名称
L-正亮氨酸, suitable for amino acid analysis, BioReagent
InChI key
LRQKBLKVPFOOQJ-YFKPBYRVSA-N
InChI
1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
SMILES string
CCCC[C@H](N)C(O)=O
product line
BioReagent
form
powder or crystals
color
white
mp
>300 °C (lit.)
suitability
suitable for amino acid analysis
application(s)
detection
Quality Level
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Application
所有氨基酸分析方法的高纯度内标物。
Other Notes
非必需氨基酸
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
L M FitzGerald et al.
Australian veterinary journal, 89(3), 95-100 (2011-02-18)
Four dogs presented with clinical signs of severe hepatic disease after consuming a commercial camel meat diet. Laboratory investigation revealed evidence of severe liver disease, including markedly increased serum alanine aminotransferase (ALT) activity and total bilirubin concentration, and prolonged clotting
Amar R Mohite et al.
The Journal of organic chemistry, 77(12), 5423-5428 (2012-05-24)
A short, concise synthesis of enantiopure, side chain-modified α-amino acids such as 4-oxo-L-norvaline, 6-oxo-L-homonorleucine, and 5-cis-alkyl prolines is described. Knoevenagel condensation of l-aminocarboxylate-derived β-ketoesters with aldehydes followed by reductive decarboxylation results in unnatural α-amino acids in good yield. A fluorescent
Haiyan Wei et al.
The journal of physical chemistry. B, 114(36), 11820-11826 (2010-08-24)
Following the studies of urea denaturation of β-hairpins using molecular dynamics, in this paper, molecular dynamics simulations of two peptides, a 35 residue three helix bundle villin headpiece protein HP-35 and its doubly norleucine-substituent mutant (Lys24Nle/Lys29Nle) HP-35 NleNle, were undertaken
Jan Pícha et al.
Journal of enzyme inhibition and medicinal chemistry, 26(2), 155-161 (2010-06-29)
Ligands containing bulky aliphatic P1 residues exhibit a high affinity towards cytosolic leucine aminopeptidase, a bizinc protease of biomedical significance. According to this specificity, a series of phosphonic and phosphinic compounds have been put forward as novel putative inhibitors of
Silvia Lisa et al.
Cellular and molecular life sciences : CMLS, 67(16), 2825-2838 (2010-05-11)
The conversion of the cellular prion protein (PrP(C)) into its disease-associated form (PrP(Sc)) involves a major conformational change and the accumulation of sulfoxidized methionines. Computational and synthetic approaches have shown that this change in the polarity of M206 and M213
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