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Merck
CN

N7627

Sigma-Aldrich

L -正缬氨酸

≥99% (TLC)

别名:

( S )-(+)-2-氨基戊酸, ( S )-2-氨基戊酸

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About This Item

线性分子式:
CH3CH2CH2CH(NH2)CO2H
CAS号:
分子量:
117.15
Beilstein:
1721162
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

产品名称

L -正缬氨酸, arginase inhibitor

质量水平

方案

≥99% (TLC)

表单

powder

颜色

white

mp

>300 °C (lit.)

应用

detection

SMILES字符串

CCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

SNDPXSYFESPGGJ-BYPYZUCNSA-N

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应用


  • 纳米药物介导TAM相关精氨酸代谢干扰,促进光动力免疫治疗。:该研究探讨了使用纳米药物干扰肿瘤相关巨噬细胞(TAM)的精氨酸代谢,增强光动力免疫治疗的疗效。L-正缬氨酸在这种代谢干扰中起着至关重要的作用(Chen et al., 2024)。

生化/生理作用

L-正缬氨酸增强活化巨噬细胞产生 NO。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
W Sosroseno et al.
Oral microbiology and immunology, 21(3), 145-150 (2006-04-22)
The aim of the present study was to determine whether or not lipopolysaccharide from Actinobacillus actinomycetemcomitans could stimulate arginase activity in a murine macrophage cell line (RAW264.7 cells). RAW264.7 cells were treated with A. actinomycetemcomitans-lipopolysaccharide or lipopolysaccharide from Escherichia coli

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