跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

N7510

Sigma-Aldrich

尼卡地平 盐酸盐

powder, ≥98%

别名:

1,4-二氢-2,6-二甲基-4-（3-硝基苯基）-3,5-吡啶二甲酸甲基 2- [甲基（苯甲基）氨基] 乙酯 盐酸盐, YC-93

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C26H29N3O6 · HCl
CAS号:
54527-84-3
分子量:
515.99
EC 号:
259-198-4
MDL编号:
MFCD00057327
UNSPSC代码:
12352200
PubChem化学物质编号:
24277856
NACRES:
NA.77

质量水平

100

方案

≥98%

表单

powder

颜色

yellow

溶解性

DMSO: ~1 mg/mL
0.1 M NaOH: insoluble
H2O: slightly soluble
methanol: soluble

创始人

EKR Therapeutics

储存温度

2-8°C

SMILES字符串

Cl[H].COC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OCCN(C)Cc3ccccc3

InChI

1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H

InChI key

AIKVCUNQWYTVTO-UHFFFAOYSA-N

基因信息

human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

正在寻找类似产品? 访问 产品对比指南

生化/生理作用

阻断 L 型电压依赖性钙通道；抗高血压药。

特点和优势

该化合物由 EKR Therapeutics 开发 。要浏览其他制药公司开发的化合物列表批准的药物/候选药物的列表， 点击这里 。

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301 + H311 + H331

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL8561
BCCJ0165
BCCH9827
BCCH8129
BCCH8128

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

T Matsuda et al.
General pharmacology, 33(2), 115-125 (1999-08-26)
The effects of nicardipine and bupivacaine on early afterdepolarizations (EADs) were investigated in rabbit sinoatrial (SA) nodes using the conventional microelectrode technique. In a nominally Ca2+ -free, Mg2+ -free solution, addition of 0.5 mM Sr2+ produced EADs following prolongation of
E M Fitzgerald
The Journal of physiology, 527 Pt 3, 433-444 (2000-09-16)
The small G-protein Ras, a critical component in the signalling pathways regulating cell growth, is involved in the tonic upregulation of voltage-dependent calcium channels (VDCCs) in rat sensory neurones. To investigate which downstream effector(s) of Ras is involved in this
T J Hibberd et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 29(10), 1-12 (2017-04-19)
Relatively little is known about the electrical rhythmicity of the whole colon, where long neural pathways are preserved. Smooth muscle electrical activity was recorded extracellularly from the serosa of isolated flat-sheet preparations consisting of the whole mouse colon (n=31). Two
GoEun Han et al.
Frontiers in neuroscience, 16, 969712-969712 (2022-11-08)
Non-rapid eye movement (NREM) sleep is tightly homeostatically regulated and essential for survival. In the electroencephalogram (EEG), oscillations in the delta (0.5-4 Hz) range are prominent during NREM sleep. These delta oscillations are, to date, the best indicator for homeostatic
Prasanna P K M Gamage et al.
Journal of cellular and molecular medicine, 22(10), 5160-5164 (2018-07-27)
Ageing is associated with impaired neuromuscular function of the terminal gastrointestinal (GI) tract, which can result in chronic constipation, faecal impaction and incontinence. Interstitial cells of cajal (ICC) play an important role in regulation of intestinal smooth muscle contraction. However
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门