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Merck
CN

N4875

Sigma-Aldrich

萘酚 AS-MX 磷酸盐

phosphatase substrate, fluorogenic, ≥99% (HPLC), powder

别名:

3-Hydroxy-2-naphtho-2′,4′-xylidide Phosphate, N-(2,4-Dimethylphenyl)-3-(phosphonooxy)-2-naphthalenecarboxamide

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About This Item

经验公式(希尔记法):
C19H18NO5P
CAS号:
分子量:
371.32
Beilstein:
6664873
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.83

product name

萘酚 AS-MX 磷酸盐, powder, ≥99% (HPLC)

质量水平

检测方案

≥99% (HPLC)

形式

powder

溶解性

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow (to Faint Brown)

储存温度

−20°C

SMILES字符串

Cc1ccc(NC(=O)c2cc3ccccc3cc2OP(O)(O)=O)c(C)c1

InChI

1S/C19H18NO5P/c1-12-7-8-17(13(2)9-12)20-19(21)16-10-14-5-3-4-6-15(14)11-18(16)25-26(22,23)24/h3-11H,1-2H3,(H,20,21)(H2,22,23,24)

InChI key

IOMLBTHPCVDRHM-UHFFFAOYSA-N

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相关类别

一般描述

萘酚AS-MX磷酸盐可溶于二噁烷,是磷酸酶的底物。

应用

萘酚AS-MX磷酸盐已用于:
  • 作为人成骨细胞碱性磷酸酶的底物
  • 小鼠胚胎干细胞(mESC)
  • 冠状面切片的荧光染色和分析

碱性磷酸酶组织化学显示的底物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Fluorescence of Naphthol AS-MX is Readily Detectable in Dioxane Mixtures
Kindl ED, et al.
Matters, 5(5), e201905000003-e201905000003 (2019)
Nanofiber/Microsphere Hybrid Matrices In Vivo for Bone Regenerative Engineering: A Preliminary Report
Nelson C, et al.
Regenerative engineering and translational medicine, 4(3), 133-141 (2018)
Developmental-like bone regeneration by human embryonic stem cell-derived mesenchymal cells.
Kuhn LT, Liu Y, Boyd NL, et al.
Tissue Engineering: Part A, 20(1-2), 365-377 (2014)
Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma
Wang X, et al.
Platelets, 29(1), 48-55 (2018)
Mitsuhiro Kinoshita et al.
Scientific reports, 11(1), 20360-20360 (2021-10-15)
Nephronectin (Npnt) is an extracellular matrix protein and ligand of integrin α8β1 known to promote differentiation of osteoblasts. A search for factors that regulate Npnt gene expression in osteoblasts revealed that phorbol 12-myristate 13-acetate (PMA), which activates protein kinase C

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