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Merck
CN

N3398

Sigma-Aldrich

S-亚硝基-N-乙酰基-DL-青霉胺

≥97%, powder

别名:

N-乙酰基-3-(硫代亚硝基)-DL-缬氨酸, S-亚硝基-N-乙酰青霉胺, SNAP

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About This Item

经验公式(希尔记法):
C7H12N2O4S
CAS号:
分子量:
220.25
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥97%

形式

powder

颜色

faint green to very dark green

溶解性

H2O: ≥2 mg/mL
DMSO: ≥20 mg/mL, clear (faint green to very dark green)

储存温度

−20°C

SMILES字符串

CC(=O)NC(C(O)=O)C(C)(C)SN=O

InChI

1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)

InChI key

ZIIQCSMRQKCOCT-UHFFFAOYSA-N

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应用

S-亚硝基-N-乙酰基-DL-青霉胺(SNAP)用于:
  • 作为亚硝酸盐生成实验中的阳性对照。
  • 阻断内源性转谷氨酰胺酶(TG2)的活性。
  • 细胞增殖实验,在细胞培养物中产生一氧化氮(NO)。

生化/生理作用

NO供体;血管扩张剂、平滑肌松弛剂、淋巴细胞激活剂。 激活可溶性鸟苷酸环化酶。
SNAP是一种亚硝基硫醇衍生物,在生理条件下释放一氧化氮(NO),从而使其成为研究NO的药理学和生理学作用的有用工具。由于SNAP具有释放NO的特性,所有其在体内体外均是有效的血管扩张剂,不易产生药理学耐受性。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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商品

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

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