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用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
cardiovascular diseases; cancer; hematological disorder
储存温度
−20°C
一般描述
醛脱氢酶（ALDH）是一类催化外源性醛和内源性醛的代谢、防止潜在反应性醛和毒性醛及其代谢物的积累的酶。除了它们在醛代谢中的作用外，ALDH酶还在其他细胞过程中起关键作用，例如细胞增殖，分化和存活。ALDH家族成员的突变与许多疾病有关，如心脏病、白内障和某些癌症。ALDH活性也可以作为某些干细胞群（包括造血干细胞和某些癌症干细胞）的标志物。
应用
醛脱氢酶活性比色检测试剂盒用于检测醛脱氢酶的活性。
特点和优势
与高通量处理系统相容。
适用性
适用于对包括组织和细胞在内的多种样品中的醛脱氢酶（ALDH）进行测定
原理
醛脱氢酶活性比色检测试剂盒提供了一种可简单直接地检测各种样品中NAD依赖性ALDH活性的方法。ALDH活性通过酶偶联法检测，其中乙醛被ALDH氧化生成NADH，NADH与探针反应，产生比色(450 nm)产物，该产物与存在的ALDH活性成比例。一单位ALDH是指该酶在室温、pH 8.0条件下每分钟产生1.0 μmM NADH的量。
警示用语：
Danger
危险声明
危险分类
Carc. 1B - Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
法规信息
含少量动物源组分生物产品
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商品
AldeRed™ 588-A detects ALDH activity in cancer stem cells, aiding in cancer research.
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