推荐产品
产品名称
3-甲基-L-组氨酸,
方案
≥98% (TLC)
质量水平
表单
powder
颜色
white to off-white
mp
254 °C
应用
detection
SMILES字符串
Cn1cncc1C[C@H](N)C(O)=O
InChI
1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1
InChI key
JDHILDINMRGULE-LURJTMIESA-N
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应用
- Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.：研究创新基因工程技术，用组氨酸类似物（如3-甲基-L-组氨酸）制出功能改进的新蛋白。治疗和工业应用前景广阔(Taylor et al., 2023)。
- Improving the enzymatic activity of l-amino acid α-ligase for imidazole dipeptide production by site-directed mutagenesis.：研究如何改进咪唑二肽的酶促合成。对于了解各种修饰（如3-甲基-L-组氨酸）的作用及其生物活性影响有重要意义(Kino et al., 2023)。
生化/生理作用
3-甲基-L-组氨酸是一种非蛋白原氨基酸，也是一项肌肉分解的指标。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
M N Goodman
The American journal of physiology, 260(5 Pt 1), E727-E730 (1991-05-01)
The metabolic response to infection includes loss of lean tissue and increased nitrogen excretion. The loss of muscle tissue during infection results in large part from accelerated skeletal muscle protein breakdown. Recent studies suggest that macrophage-derived products secreted during infection
E Roth et al.
Clinical chemistry, 31(8), 1305-1309 (1985-08-01)
We measured amino acid concentrations in plasma and skeletal muscle of three groups of patients with acute hemorrhagic pancreatitis: (a) patients without secondary organ lesions, (b) patients also suffering from kidney damage, and (c) patients in whom the pancreatitis was
Elin Chorell et al.
Journal of proteome research, 8(6), 2966-2977 (2009-03-26)
We have investigated whether postexercise ingestion of carbohydrates in combination with proteins generates a different systemic metabolic response, as compared to the sole ingestion of carbohydrate or water, in the early recovery phase following exercise. In addition, metabolic patterns related
Rokhsareh F Vesali et al.
Clinical science (London, England : 1979), 118(6), 421-427 (2009-09-16)
The human endotoxin model has been used to study the early phase of sepsis. The aim of the present study was to assess leg muscle protein kinetics after an endotoxin challenge given to healthy human volunteers. Six healthy male subjects
Melanie J Edwards et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 180(2), 247-257 (2009-09-04)
We fed common brushtail possums artificial diets containing a buffer and the plant secondary metabolite (PSM), orcinol, to test the hypothesis that organic acids, common products of PSM metabolism, limit feeding by common brushtail possums (Trichosurus vulpecula). We introduced several
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