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Merck
CN

M5171

Sigma-Aldrich

S-Methyl-L-thiocitrulline acetate salt

≥98% (TLC)

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About This Item

经验公式(希尔记法):
C7H15N3O2S · C2H4O2
分子量:
265.33
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32

质量水平

方案

≥98% (TLC)

储存温度

−20°C

SMILES字符串

CC(O)=O.CSC(=N)NCCC[C@H](N)C(O)=O

InChI

1S/C7H15N3O2S.C2H4O2/c1-13-7(9)10-4-2-3-5(8)6(11)12;1-2(3)4/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12);1H3,(H,3,4)/t5-;/m0./s1

InChI key

XUKPZPRDNPUAJY-JEDNCBNOSA-N

生化/生理作用

Potent inhibitor of inducible nitric oxide synthase with preference for constitutive (neuronal) over inducible (endothelial) NOS.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Narayanan et al.
Journal of medicinal chemistry, 37(7), 885-887 (1994-04-01)
Nitric oxide synthase catalyzes the NADPH- and O2-dependent conversion of L-arginine to L-citrulline and nitric oxide. L-Thiocitrulline, L-homothiocitrulline, and S-methyl-L-thiocitrulline, novel citrulline analogs, have been synthesized and are shown to be potent inhibitors of both the constitutive brain and the
Liliana M Sanmarco et al.
Nature, 611(7937), 801-809 (2022-10-21)
Genome-wide association studies have identified risk loci linked to inflammatory bowel disease (IBD)1-a complex chronic inflammatory disorder of the gastrointestinal tract. The increasing prevalence of IBD in industrialized countries and the augmented disease risk observed in migrants who move into

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