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Merck
CN

NOS3

nitric oxide synthase 3 (endothelial cell)

Synonyms:
ECNOS, eNOS
Species:
Human NOS3 (4846), Mouse Nos3 (18127), Rat Nos3 (24600), sheep NOS3 (443073), dog NOS3 (403784), domestic cat NOS3 (101096463), naked mole-rat Nos3 (101711110), Horse NOS3 (100063339), Domestic Rabbit NOS3 (100009498), domestic guinea pig Nos3 (100135577) ...More
UniProtKB ID:
P29474, A0S0A7, A0S0A8, A8KA63, B2RCQ1, E9PFR2, Q13662, Q14251
Gene ID:
  • Human(4846) Summary: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(18127) nitric oxide synthase 3, endothelial cell
  • Rat(24600) nitric oxide synthase 3, endothelial cell
  • sheep(443073) nitric oxide synthase 3 (endothelial cell)
  • dog(403784) nitric oxide synthase 3 (endothelial cell)
  • domestic cat(101096463) nitric oxide synthase 3 (endothelial cell)
  • naked mole-rat(101711110) nitric oxide synthase 3 (endothelial cell)
  • Horse(100063339) nitric oxide synthase 3 (endothelial cell)
  • Domestic Rabbit(100009498) nitric oxide synthase 3 (endothelial cell)
  • domestic guinea pig(100135577) nitric oxide synthase 3, endothelial cell
  • cow(287024) nitric oxide synthase 3 (endothelial cell)
  • chicken(100858754) endothelial nitric oxide synthase 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
P8765
Ammonium pyrrolidinedithiocarbamate, ~99%,
Species
human
M5250
Melatonin, powder, ≥98% (TLC),
Species
human
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Species
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5700381
Anti-Phospho-eNOS-S1177 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
SAB5700382
Anti-Phospho-eNOS-T495 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
SAB5700355
Anti-Phospho-eNOS-S1177 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
AB16301
Anti-Nitric Oxide Synthase III Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
western blot
ABS1631
Anti-phospho-eNOS (Ser602), from rabbit,
Species Reactivity
bovine, human
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
A51807
2-Amino-4,6-dimethylpyridine, 99%,
Species
human
W4262
1400W dihydrochloride, >98%, solid,
Species
human
123080
2-Amino-4-methylpyridine, 99%,
Species
rat, human
O3636
1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, powder,
Species
human
T7313
1-[2-(Trifluoromethyl)phenyl]imidazole, ,
Species
human

Kits

Product Number
Description
Species
FCANOS1
Nitric Oxide Synthase Detection System, Fluorimetric, sufficient for 200 reactions,
Species
human