形式
powder
质量水平
mp
188-194 °C (lit.)
抗生素抗菌谱
fungi
作用机制
enzyme | inhibits
创始人
Celgene
储存温度
−20°C
SMILES字符串
OCCS(O)(=O)=O.OCCS(O)(=O)=O.NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
InChI
1S/C19H24N4O2.2C2H6O4S/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;2*3-1-2-7(4,5)6/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*3H,1-2H2,(H,4,5,6)
InChI key
YBVNFKZSMZGRAD-UHFFFAOYSA-N
基因信息
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907) , NOS1(4842) , NOS2(4843) , NOS2B(201288) , NOS2C(645740) , NOS3(4846)
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警示用语：
Warning
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
I J Reynolds et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 12(3), 970-975 (1992-03-01)
Acquired immunodeficiency syndrome (AIDS) is frequently associated with dementia. The wide spectrum of neurological abnormalities associated with this dementia may involve a neurotoxin that activates the NMDA subtype of glutamate receptor in neurons. We have found that the antimicrobial agent
Anti-leishmanial lindenane sesquiterpenes from Hedyosmum angustifolium
Acebey L, et al.
Planta Medica, 76(04), 365-368 (2010)
Drug-induced functional cardiotoxicity screening in stem cell-derived human and mouse cardiomyocytes: effects of reference compounds
Himmel HM
Journal of Pharmacological and Toxicological Methods, 68(1), 97-111 (2013)
Reduced Antimony Accumulation in ARM58-Overexpressing Leishmania infantum.
Schafer C, et al.
Antimicrobial Agents and Chemotherapy, 58(3), 1565-1574 (2014)
Lucia Acebey et al.
Planta medica, 76(4), 365-368 (2009-10-16)
The aim of this work is the isolation of anti-leishmanial compounds from the ethyl acetate extracts of the bark of HEDYOSMUM ANGUSTIFOLIUM. We have successfully isolated and characterized five sesquiterpenes: one new compound (oxyonoseriolide, 1), one compound isolated for the
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