product name
3-Methoxy-L-tyrosine monohydrate, powder
检测方案
≥98% (HPLC)
质量水平
形式
powder
应用
detection
储存温度
2-8°C
SMILES字符串
COc1cc(C[C@H](N)C(O)=O)ccc1O
InChI
1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)/t7-/m0/s1
InChI key
PFDUUKDQEHURQC-ZETCQYMHSA-N
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生化/生理作用
3-Methoxy-L-tyrosine is a metabolite of L-Dopa.
The major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Chiara Muzzi et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(4), 253-258 (2007-12-26)
Levodopa is the medication of choice for Parkinson's disease. The biological complexity of levodopa and of its main derivatives makes their determination important in the clinical field. The aim of this study was to develop an HPLC method for the
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