M4159
亚甲蓝 水合物
suitable for nucleic acid staining, BioReagent
别名:
3,7-双(二甲基氨基)吩噻嗪-5-鎓氯化物, 亚甲蓝, 亚甲蓝一水合物, 核酸染色试剂
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关于此项目
经验公式（希尔记法）:
C16H18ClN3S · xH2O
化学文摘社编号:
分子量:
319.85 (anhydrous basis)
UNSPSC Code:
12171500
NACRES:
NA.52
PubChem Substance ID:
EC Number:
200-515-2
Beilstein/REAXYS Number:
3599847
MDL number:
产品名称
亚甲蓝 水合物, suitable for nucleic acid staining, BioReagent
InChI key
WQVSELLRAGBDLX-UHFFFAOYSA-M
InChI
1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
SMILES string
O.[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C
grade
Molecular Biology
product line
BioReagent
form
powder
technique(s)
nucleic acid detection: suitable
solubility
water: 1 mg/mL (dark blue)
suitability
suitable for nucleic acid staining
storage temp.
room temp
Quality Level
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Application
亚甲基蓝水合物适合用作琼脂糖和聚丙烯酰胺凝胶电泳（PAGE）的核酸染液。通过使用克隆形成试验，被用于对4T1肿瘤细胞进行染色以研究肿瘤细胞的转移。亚甲基蓝水合物晶体通过被包封在脱铁蛋白纳米笼中，可用于抗肿瘤细胞的光动力学疗法。
Features and Benefits
- 比溴化乙锭染色的危害更小
- 可在可见光下观察
- 快速且易于使用。
General description
亚甲蓝是一种杂环芳香化学品，呈深绿色固体粉末状，在水溶液中会变为蓝色。它在许多不同的组织学过程以及分子生物学实验室中被用作染色剂。
Ariane Felgenträger et al.
BioMed research international, 2013, 482167-482167 (2013-03-20)
Photodynamic inactivation of bacteria (PIB) by efficient singlet oxygen photosensitizers might be a beneficial alternative to antibiotics in the struggle against multiresistant bacteria. Phenothiazinium dyes belong to the most prominent classes of such sensitizers due to their intense absorption in
Resolution of multiple ribonucleic acid species by polyacrylamide gel electrophoresis.
A C Peacock et al.
Biochemistry, 6(6), 1818-1827 (1967-06-01)
Angela L Davis et al.
International journal of molecular sciences, 14(2), 4185-4202 (2013-02-23)
Repurposing approved and abandoned non-oncological drugs is an alternative developmental strategy for the identification of anticancer therapeutics that has recently attracted considerable attention. Due to the essential role of the cellular heat shock response in cytoprotection through the maintenance of
Young-Sharp, D. and Kumar, R.
Technique, 1, 183-183 (1989)
Fei Yan et al.
Photochemistry and photobiology, 86(3), 662-666 (2010-02-06)
This study reports that photosensitizers encapsulated in supramolecular protein cages can be internalized by tumor cells and can deliver singlet oxygen intracellularly for photodynamic therapy (PDT). As an alternative to other polymeric and/or inorganic nanocarriers and nanoconjugates, which may also
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