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生物来源
rabbit
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 72 kDa (proform)
种属反应性
mouse, bovine, rat, human
浓度
~1 mg/mL
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 10-20 μg/mL
western blot: 5-10 μg/mL
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MMP2(4313)
特异性
Recognizes MMP-2, cytoplasmic localization. Shows no cross-reactivity with the pro and active forms of other MMPs.
免疫原
synthetic peptide from the second half of human MMP-2 (Gelatinase-A, 72 kDa Gelatinase). The immunogen is synthesized as a 631 amino acid proenzyme that is activated by cleavage of the the first 80 amino acids.
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
外形
Solution in 10 mM phosphate buffered saline, pH 7.4, containing 0.2% bovine serum albumin and 0.09% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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法规信息
新产品
Andreea Iren Serban et al.
PloS one, 11(3), e0152376-e0152376 (2016-03-26)
AGEs accumulation in the skin affects extracellular matrix (ECM) turnover and triggers diabetes associated skin conditions and accelerated skin aging. The receptor of AGEs (RAGE) has an essential contribution to cellular dysfunction driven by chronic inflammatory responses while TGF-β1 is
Manikantan S Kiran et al.
Vascular cell, 3(1), 6-6 (2011-02-26)
The mechanism of cell-cell contact dependent regulation of pericellular proteolysis in angiogenesis was examined by studying the expression of MMPs using isolated HUVECs in culture. Zymography, Immunoblot and RT-PCR analysis showed that the production and secretion of matrixmetalloproteinase-2 and matrixmetalloproteinase-9
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