MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
别名:
CLG4, CLG4A, MMP-II, MONA, TBE-1
物种:
Human MMP2 (4313), Mouse Mmp2 (17390), Rat Mmp2 (81686), naked mole-rat Mmp2 (101696977), cow MMP2 (282872), sheep MMP2 (443115), chicken MMP2 (386583), domestic guinea pig Mmp2 (100719361), dog MMP2 (403733), Zebrafish mmp2 (337179) ...展开
UniProtKB ID:
基因ID:
- Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(17390) matrix metallopeptidase 2
- Rat(81686) matrix metallopeptidase 2
- naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- Zebrafish(337179) matrix metalloproteinase 2
- Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- fruit fly(35997) Matrix metalloproteinase 2
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ELISA
Antibodies
货号
说明
物种反应性
应用
抗CFT抗MMP-2抗体，a.a。468-483 hMMP2，克隆 42-5D11, clone 42-5D11, Chemicon®, from mouse,
物种反应性
bovine, horse, human, mouse, pig, rabbit, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-MMP2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
物种反应性
bovine, human, mouse, rat
应用
Anti-MMP-2 Antibody, pro and active form, clone VB3, clone VB3, Chemicon®, from mouse,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti- MMP2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
基质金属蛋白酶-2 人, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
物种
human
基质金属蛋白酶2 来源于小鼠, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
物种
mouse, rat