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Merck
CN

M3529

Sigma-Aldrich

L-蛋氨酸对硝基苯胺

≥98% (TLC), suitable for ligand binding assays

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About This Item

经验公式(希尔记法):
C11H15N3O3S
CAS号:
分子量:
269.32
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

product name

L-蛋氨酸对硝基苯胺,

检测方案

≥98% (TLC)

质量水平

形式

powder

技术

ligand binding assay: suitable

颜色

white to faint yellow

储存温度

−20°C

SMILES字符串

CSCC[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C11H15N3O3S/c1-18-7-6-10(12)11(15)13-8-2-4-9(5-3-8)14(16)17/h2-5,10H,6-7,12H2,1H3,(H,13,15)/t10-/m0/s1

InChI key

PLBWRAWSHVJPTL-JTQLQIEISA-N

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生化/生理作用

L-蛋氨酸对硝基苯胺是一种hMetAP2底物。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Sanghamitra Mitra et al.
Analytical biochemistry, 357(1), 43-49 (2006-07-18)
A direct and convenient spectrophotometric assay has been developed for methionine aminopeptidases (MetAPs). The method employs the hydrolysis of a substrate that is a methionyl analogue of p-nitroaniline (L-Met-p-NA), which releases the chromogenic product p-nitroaniline. This chromogenic product can be
G Yang et al.
Biochemistry, 40(35), 10645-10654 (2001-08-29)
The steady-state kinetics of a full-length and truncated form of the type 2 human methionine aminopeptidase (hMetAP2) were analyzed by continuous monitoring of the amide bond cleavage of various peptide substrates and methionyl analogues of 7-amido-4-methylcoumarin (AMC) and p-nitroaniline (pNA)
R A Cowman et al.
Journal of dental research, 70(12), 1508-1515 (1991-12-01)
Intact cells of Streptococcus sanguis ATCC 10556 possessed arylaminopeptidases exhibiting activity toward the nitroanilide (NA) derivatives of leucine, alanine, methionine, arginine, or lysine. Weak hydrolytic activity was observed in assays with the NA derivatives of valine, proline, glycine, or glutamic

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