M3168
4-Methylumbelliferyl phosphate
alkaline phosphatase substrate, liquid
别名:
4-methylumbelliferone phosphate Liquid Substrate System
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
EC Number:
222-137-7
MDL number:
产品名称
4-甲基伞形酮磷酸酯 (4-MUP) 液体底物系统, liquid
SMILES string
CC1=CC(=O)Oc2cc(OP(O)(O)=O)ccc12
InChI key
BCHIXGBGRHLSBE-UHFFFAOYSA-N
InChI
1S/C10H9O6P/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14/h2-5H,1H3,(H2,12,13,14)
form
liquid
storage temp.
2-8°C
Quality Level
Analysis Note
4-MUP 荧光可在 360 nm 激发和 440 nm 发射下测量。也可使用紫外光源观察荧光终产物。
Application
4-甲基伞形磷酸酯（4-MUP）液体底物系统已被用作酶联免疫吸附测定（ELISA）中碱性磷酸盐的荧光底物。它也已被用于分泌的胚胎碱性磷酸酶（SEAP）活性测定中。
General description
4-甲基伞形酮磷酸酯 (4-MUP) 是碱性磷酸酶的底物，碱性磷酸酶形成可溶性荧光物质甲基伞形酮。4-MUP 液体底物系统在即用型试剂中结合了 4-MUP 和缓冲液。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Activation of NF-kappaB by rank requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase identification of a novel TRAF6 interaction motif
Darnay BG, et al.
The Journal of biological chemistry, 274(12), 7724-7731 (1999)
Degree of hydrolysis and antigenicity of buffalo alpha S1 casein and its hydrolysates in children with cow milk allergy
Ahmad N, et al.
Food and agricultural immunology, 27(1), 87-98 (2016)
Modification of pasta structure induced by high drying temperatures. Effects on the in vitro digestibility of protein and starch fractions and the potential allergenicity of protein hydrolysates
Petitot M, et al.
Food Chemistry, 116(2), 401-412 (2009)
Assessment of allergenicity of diploid and hexaploid wheat genotypes: Identification of allergens in the albumin/globulin fraction
Larre C, et al.
Journal of Proteomics, 74(8), 1279-1289 (2011)
Christopher P Holmes et al.
Bioorganic & medicinal chemistry letters, 18(11), 3382-3385 (2008-04-30)
As part of a program to develop better PTP1B fluorogenic substrates that more closely mimic the functionality found in the natural substrate, we have prepared and evaluated nine novel analogs of 4-methylumbelliferone phosphate (MUP) with a variety of additional groups
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