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Merck
CN

M1275

Sigma-Aldrich

萘普生 钠

98.0-102.0%

别名:

(S)-6-甲氧基-α-甲基-2-萘乙酸 钠盐

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About This Item

经验公式(希尔记法):
C14H13NaO3
CAS号:
分子量:
252.24
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic (organic)

质量水平

检测方案

98.0-102.0%

形式

powder

溶解性

water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

创始人

Bayer

SMILES字符串

[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O

InChI

1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1

InChI key

CDBRNDSHEYLDJV-FVGYRXGTSA-M

基因信息

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一般描述

萘普生属于苯乙酸类非甾体抗炎药 (NSAID)。

应用

萘普生钠已被用于评价牛血清白蛋白和人血清白蛋白生物分子相互作用的热力学。其也被用于评价其降低脊髓背角神经元对伤害性膝关节旋转反应的效率。

生化/生理作用

萘普生最好与血清白蛋白结合。与 R-异构体相比,萘普生的 S-异构体作为抗炎药物的潜力是前者的 28 倍。发现 R-异构体是一种肝脏毒素,可导致胃肠道疾病。
环加氧酶(前列腺素 H 合成酶 1 和 2)抑制剂。

特点和优势

该化合物由Bayer开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 1A

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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