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PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

别名:

COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2

物种:

Human PTGS2 (5743), Mouse Ptgs2 (19225), Rat Ptgs2 (29527), Goat PTGS2 (100860905), cow PTGS2 (282023), Horse PTGS2 (791253), domestic cat PTGS2 (100126581), dog PTGS2 (442942), Domestic Rabbit PTGS2 (100009248), sheep PTGS2 (443460) ...展开

UniProtKB ID:

P35354, A8K802, Q16876

基因ID:

Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Mouse(19225) prostaglandin-endoperoxide synthase 2
Rat(29527) prostaglandin-endoperoxide synthase 2
Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

货号

说明

物种

人COX-2 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,

物种

human

Antibodies

货号

说明

物种反应性

应用

Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,

物种反应性

mouse

应用

immunohistochemistry
western blot

抗-COX2 兔抗, affinity isolated antibody,

物种反应性

human

应用

ELISA
immunofluorescence
immunohistochemistry
western blot

Anti-Cox2 antibody produced in rabbit, ,

物种反应性

human, mouse, rat

应用

immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot

抗-COX2 兔抗, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

物种反应性

human

应用

immunofluorescence
immunohistochemistry

Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,

物种反应性

human

应用

immunohistochemistry

Small Molecule - Blocker

货号

说明

物种

N-对-甲苯磺酰基-L-苯基乙基氯甲基酮, ≥97% (TLC), powder,

物种

human

Small Molecule - Inhibitor

货号

说明

物种

卡洛芬, ≥97% (HPLC),

物种

human

Aceclofenac, ≥98% (HPLC),

物种

human

塞来昔布, United States Pharmacopeia (USP) Reference Standard,

物种

human

Meloxicam sodium salt hydrate, ≥98% (HPLC),

物种

human

卡洛芬, United States Pharmacopeia (USP) Reference Standard,

物种

human

Proteins

货号

说明

物种

环氧化酶 2 人, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,

物种

human

esiRNA

货号

说明

物种

MISSION^® esiRNA, targeting mouse Ptgs2,

物种

mouse

MISSION^® esiRNA, targeting human PTGS2,

物种

human