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Merck
CN

M1126

Sigma-Aldrich

L -甲硫氨酸亚砜

≥98% (TLC)

别名:

L -2-氨基-4-(甲基亚磺酰基)丁酸

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About This Item

经验公式(希尔记法):
C5H11NO3S
CAS号:
分子量:
165.21
Beilstein:
4129939
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

L -甲硫氨酸亚砜,

方案

≥98% (TLC)

质量水平

表单

powder

颜色

white to off-white

mp

255 °C

应用

detection
peptide synthesis

SMILES字符串

CS(=O)CC[C@H](N)C(O)=O

InChI

1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10?/m0/s1

InChI key

QEFRNWWLZKMPFJ-YGVKFDHGSA-N

基因信息

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应用

  • DmsABC硫氧化物还原酶是流感嗜血杆菌中次氯酸盐诱导的新型胞外应激防御系统必不可少的一种成分。该研究阐明了L-甲硫氨酸亚砜还原酶在细菌防御系统中的酶促作用,强调了其在抗微生物策略开发领域中的生物技术应用(Nasreen et al., 2024)。

生化/生理作用

L-甲硫氨酸亚砜是谷氨酸盐的结构类似物,可作为底物用于研究各种甲硫氨酸亚砜还原酶 (s) 的特异性和动力学。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Gabriel Javitt et al.
Antioxidants & redox signaling, 33(10), 665-678 (2020-06-11)
Aims: The post-translational oxidation of methionine to methionine sulfoxide (MetSO) is a reversible process, enabling the repair of oxidative damage to proteins and the use of sulfoxidation as a regulatory switch. MetSO reductases catalyze the stereospecific reduction of MetSO. One
Martina I Boxler et al.
Journal of proteome research, 16(9), 3310-3320 (2017-07-20)
3,4-Methylenedioxymethamphetamine (MDMA; "ecstasy") is widely consumed recreationally. Little is known about its effects on the human metabolome. Mapping biochemical changes after drug exposure can complement traditional approaches by revealing potential biomarkers of organ toxicity or discovering new metabolomic features in
Sofia Lourenço Dos Santos et al.
Antioxidants (Basel, Switzerland), 7(12) (2018-12-14)
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated enzymatic repair systems. Oxidation
Benjamin P Barré et al.
Genome research, 30(5), 697-710 (2020-04-12)
Aging varies among individuals due to both genetics and environment, but the underlying molecular mechanisms remain largely unknown. Using a highly recombined Saccharomyces cerevisiae population, we found 30 distinct quantitative trait loci (QTLs) that control chronological life span (CLS) in
Jung Min Kim et al.
Scientific reports, 7(1), 11642-11642 (2017-09-16)
Despite significant advances on fluorescent labeling of target proteins to study their structural dynamics and function, there has been need for labeling with high quantum yield ensuring high sensitivity and selectivity without sacrificing the biological function of the protein. Here

实验方案

Separation of L-Methionine sulfone; L-Methionine sulfoximine; L-Methionine sulfoxide

Chromatograms

application for HPLC

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