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质量水平
形式
powder
组成
Peptide content, ~60%
浓度
≥55% (peptide)
颜色
white
储存温度
−20°C
SMILES字符串
NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O
InChI
1S/C30H62N10O6/c31-16-6-1-11-21(36)26(41)37-22(12-2-7-17-32)27(42)38-23(13-3-8-18-33)28(43)39-24(14-4-9-19-34)29(44)40-25(30(45)46)15-5-10-20-35/h21-25H,1-20,31-36H2,(H,37,41)(H,38,42)(H,39,43)(H,40,44)(H,45,46)
InChI key
IXPHOHNWDLRFJH-UHFFFAOYSA-N
Amino Acid Sequence
Lys-Lys-Lys-Lys
生化/生理作用
Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids.
T M Lohman et al.
Biochemistry, 19(15), 3522-3530 (1980-07-22)
Marisa Claudia Alvarez et al.
Clinical epigenetics, 10(1), 139-139 (2018-11-10)
In the present study, we investigated the molecular mechanisms underlying the pro-apoptotic effects of quercetin (Qu) by evaluating the effect of Qu treatment on DNA methylation and posttranslational histone modifications of genes related to the apoptosis pathway. This study was
M Roux et al.
European biophysics journal : EBJ, 16(5), 267-273 (1988-01-01)
The interaction of cationic pentalysine with phospholipid membranes was studied by using phosphorus and deuterium Nuclear Magnetic Resonance (NMR) of headgroup deuterated dimyristoyl phosphatidylcholine (DMPC) and dimyristoyl phosphatidylserine (DMPS). In the absence of pentalysine, some of the deuterium and phosphorus
Dan Zhao et al.
Journal of neuroinflammation, 14(1), 234-234 (2017-12-05)
It has been shown that chronic stress-induced depression is associated with exaggerated inflammatory response in the brain. Alpha7 nicotinic acetylcholine receptors (α7nAChRs) regulate the cholinergic anti-inflammatory pathway, but the role of cholinergic signaling and α7nAChR in chronic stress has not
Fabiana Perocchi et al.
Nucleic acids research, 35(19), e128-e128 (2007-09-28)
Recent transcription profiling studies have revealed an unanticipatedly large proportion of antisense transcription across eukaryotic and bacterial genomes. However, the extent and significance of antisense transcripts is controversial partly because experimental artifacts are suspected. Here, we present a method to
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