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经验公式(希尔记法):
C18H38N6O4
化学文摘社编号:
分子量:
402.53
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
Lys-Lys-Lys, ≥97% (TLC)
SMILES string
NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O
InChI
1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)
InChI key
WBSCNDJQPKSPII-UHFFFAOYSA-N
assay
≥97% (TLC)
form
powder
composition
Peptide content, ~60%
color
white to off-white
storage temp.
−20°C
Quality Level
Application
三赖氨酸(tri-L-赖氨酸,lys3)、四赖氨酸(tetra-L-赖氨酸,lys4)和五赖氨酸(penta-L-赖氨酸,lys5)等短的聚-L-赖氨酸多肽属于可用于构建基因传递载体和DNA纳米颗粒的阳离子部分。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Aboli A Rane et al.
PloS one, 6(6), e21571-e21571 (2011-07-07)
Several injectable materials have been shown to preserve or improve cardiac function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction (MI). However, it is unclear as to whether it is the structural support or the bioactivity
Peter G Millili et al.
Microscopy research and technique, 73(9), 866-877 (2010-03-17)
Polycationic polymers have been used to condense therapeutic DNA into submicron particles, offering protection from shear-induced or enzymatic degradation. However, the spontaneous nature of this self-assembly process gives rise to the formation of multimolecular aggregates, resulting in significant polyplex heterogeneity.
Sandrine Perrier et al.
Journal of the American Chemical Society, 128(17), 5703-5710 (2006-04-28)
Formation of DNA-protein cross-links involving the initial formation of a guanine radical cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT oligonucleotide in aerated aqueous solution in the presence of the KKK tripeptide was performed. We have shown
Magdalena Stobiecka et al.
Biomaterials, 32(12), 3312-3321 (2011-02-11)
In view of the prospective applications of polyamine coatings in functional gold nanoparticles for use as carriers in gene delivery systems, in tissue repair and as bactericidal and virucidal non-toxic vehicle, we have investigated the interactions of poly-l-lysine (PLL) with
Erik Wernersson et al.
The journal of physical chemistry. B, 114(36), 11934-11941 (2010-08-24)
Domains rich in cationic amino acids are ubiquitous in peptides with the ability to cross cell membranes, which is likely related to the binding of such polypeptides to anionic groups on the membrane surface. To shed more light on these
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