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Merck
CN

L8901

Sigma-Aldrich

Lys-Lys-Lys

≥97% (TLC)

别名:

三赖氨酸

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About This Item

经验公式(希尔记法):
C18H38N6O4
CAS号:
分子量:
402.53
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

product name

Lys-Lys-Lys, ≥97% (TLC)

质量水平

检测方案

≥97% (TLC)

形式

powder

组成

Peptide content, ~60%

颜色

white to off-white

储存温度

−20°C

SMILES字符串

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)

InChI key

WBSCNDJQPKSPII-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys

应用

三赖氨酸(tri-L-赖氨酸,lys3)、四赖氨酸(tetra-L-赖氨酸,lys4)和五赖氨酸(penta-L-赖氨酸,lys5)等短的聚-L-赖氨酸多肽属于可用于构建基因传递载体和DNA纳米颗粒的阳离子部分。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Sandrine Perrier et al.
Journal of the American Chemical Society, 128(17), 5703-5710 (2006-04-28)
Formation of DNA-protein cross-links involving the initial formation of a guanine radical cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT oligonucleotide in aerated aqueous solution in the presence of the KKK tripeptide was performed. We have shown
Peter G Millili et al.
Microscopy research and technique, 73(9), 866-877 (2010-03-17)
Polycationic polymers have been used to condense therapeutic DNA into submicron particles, offering protection from shear-induced or enzymatic degradation. However, the spontaneous nature of this self-assembly process gives rise to the formation of multimolecular aggregates, resulting in significant polyplex heterogeneity.
Aboli A Rane et al.
PloS one, 6(6), e21571-e21571 (2011-07-07)
Several injectable materials have been shown to preserve or improve cardiac function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction (MI). However, it is unclear as to whether it is the structural support or the bioactivity
Yong Joo Jun et al.
Bioorganic & medicinal chemistry letters, 17(11), 2975-2978 (2007-04-13)
In order to develop a new gene delivery vector, a novel cationic poly(organophosphazene) was synthesized by stepwise nucleophilic substitutions of poly(dichlorophosphazene) with a hydrophilic methoxy-poly(ethylene glycol) (MPEG) as a shielding group and a branched tetra(L-lysine), LysLys(LysEt)(2), as a cationic moiety.
Ignác Capek
Advances in colloid and interface science, 163(2), 123-143 (2011-03-09)
Many biomolecules have specific binding properties in the nanostructure formation; they are attractive materials for nanotechnology. One such promising construction material for growing a well-defined nanostructure is deoxyribonucleic acid, due to its π-electron hydrophobic core and predictable recognition attributed to

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