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Merck
CN

L8901

Sigma-Aldrich

Lys-Lys-Lys

≥97% (TLC)

别名:

三赖氨酸

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About This Item

经验公式(希尔记法):
C18H38N6O4
CAS号:
分子量:
402.53
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

Lys-Lys-Lys, ≥97% (TLC)

质量水平

方案

≥97% (TLC)

表单

powder

组成

Peptide content, ~60%

颜色

white to off-white

储存温度

−20°C

SMILES字符串

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)

InChI key

WBSCNDJQPKSPII-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys

应用

三赖氨酸(tri-L-赖氨酸,lys3)、四赖氨酸(tetra-L-赖氨酸,lys4)和五赖氨酸(penta-L-赖氨酸,lys5)等短的聚-L-赖氨酸多肽属于可用于构建基因传递载体和DNA纳米颗粒的阳离子部分。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Aboli A Rane et al.
PloS one, 6(6), e21571-e21571 (2011-07-07)
Several injectable materials have been shown to preserve or improve cardiac function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction (MI). However, it is unclear as to whether it is the structural support or the bioactivity
Sandrine Perrier et al.
Journal of the American Chemical Society, 128(17), 5703-5710 (2006-04-28)
Formation of DNA-protein cross-links involving the initial formation of a guanine radical cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT oligonucleotide in aerated aqueous solution in the presence of the KKK tripeptide was performed. We have shown
Peter G Millili et al.
Microscopy research and technique, 73(9), 866-877 (2010-03-17)
Polycationic polymers have been used to condense therapeutic DNA into submicron particles, offering protection from shear-induced or enzymatic degradation. However, the spontaneous nature of this self-assembly process gives rise to the formation of multimolecular aggregates, resulting in significant polyplex heterogeneity.
Yong Joo Jun et al.
Bioorganic & medicinal chemistry letters, 17(11), 2975-2978 (2007-04-13)
In order to develop a new gene delivery vector, a novel cationic poly(organophosphazene) was synthesized by stepwise nucleophilic substitutions of poly(dichlorophosphazene) with a hydrophilic methoxy-poly(ethylene glycol) (MPEG) as a shielding group and a branched tetra(L-lysine), LysLys(LysEt)(2), as a cationic moiety.
Erik Wernersson et al.
The journal of physical chemistry. B, 114(36), 11934-11941 (2010-08-24)
Domains rich in cationic amino acids are ubiquitous in peptides with the ability to cross cell membranes, which is likely related to the binding of such polypeptides to anionic groups on the membrane surface. To shed more light on these

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