L8000
L-亮氨酸
≥98% (HPLC), suitable for ligand binding assays
别名:
(S)-2-氨基-4-甲基戊酸
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-522-0
MDL number:
Beilstein/REAXYS Number:
1721722
产品名称
L-亮氨酸, reagent grade, ≥98% (HPLC)
InChI key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
SMILES string
CC(C)C[C@H](N)C(O)=O
grade
reagent grade
assay
≥98% (HPLC)
form
powder
technique(s)
ligand binding assay: suitable
impurities
isoleucine and methionine, essentially free
color
white to off-white
mp
>300 °C (lit.)
application(s)
peptide synthesis
Quality Level
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Application
L-亮氨酸已被用作雷帕霉素（mTOR）机制靶标的激动剂，以确定AMPK/mTOR途径是否参与小檗碱介导的J774A.1细胞自噬。它也被用于转化后细胞的选择。
Biochem/physiol Actions
亮氨酸是一种非生糖必需氨基酸。它是一种支链氨基酸，是蛋白质的结构组分。亮氨酸对胰岛素的释放可产生积极影响，从而消除血液中的毒性糖。亮氨酸的降解会导致酮体的形成。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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