推荐产品
生物来源
Escherichia coli (O55:B5)
质量水平
表单
lyophilized powder
纯化方式
gel-filtration chromatography
杂质
<3% Protein
颜色
white to faint gray
溶解性
water: soluble
运输
ambient
储存温度
2-8°C
正在寻找类似产品? 访问 产品对比指南
相关类别
一般描述
这种产品是从大肠杆菌中提取的大肠杆菌血清型O55：B5，通过凝胶过滤纯化。源菌株是CDC 1644-70。脂多糖O55：B5已被用于以1纳克/毫升刺激人腹膜巨噬细胞，并以1-100纳克/毫升刺激马腹膜巨噬细胞。
应用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征组分。脂多糖及其脂质 A 部分通过 Toll 样受体 4（TLR4）刺激先天免疫系统的细胞，Toll 样受体 4是 Toll 样受体蛋白家族的成员，其识别常见的病原体相关分子模式（PAMP）。
生化/生理作用
脂多糖位于膜的外层，在非包膜菌株中，暴露在细胞表面。它们有助于外膜的完整性，保护细胞免受胆盐和亲脂性抗生素的作用。
制备说明
该产品可溶于水（5毫克/毫升）或细胞培养基（1毫克/毫升），产生一种朦胧的淡黄色溶液。在涡旋并升温至70-80 oC温度后，在盐水中获得了更浓但仍模糊的溶液（20毫克/毫升）脂多糖是在每种溶剂中形成胶束的分子。在水和磷酸盐缓冲盐水中观察到混浊的溶液。有机溶剂不能提供更清晰的溶液。甲醇产生带有漂浮物的混浊悬浮液，而水产生均匀混浊的溶液。
相关产品
产品编号
说明
价格
警示用语：
Danger
危险声明
危险分类
Acute Tox. 2 Oral
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Yunru Ren et al.
Water research, 154, 153-161 (2019-02-21)
Aerosolized reclaimed water can cause inflammatory responses in lung after inhalation, and endotoxin has been identified as the main inducer. Since the effects of disinfection treatments on endotoxins had conflicting results, this study explored the changes of endotoxin activity and
John Bienenstock et al.
PloS one, 8(10), e76236-e76236 (2013-10-08)
Human milk oligosaccharides (HMO) are being studied by different groups exploring a broad range of potential beneficial effects to the breastfed infant. Many of these effects have been attributed to a growth promotion effect on certain gut organisms such as
Francisco J Quintana et al.
PloS one, 3(10), e3509-e3509 (2008-10-24)
B-cells integrate antigen-specific signals transduced via the B-cell receptor (BCR) and antigen non-specific co-stimulatory signals provided by cytokines and CD40 ligation in order to produce IgG antibodies. Toll-like receptors (TLRs) also provide co-stimulation, but the requirement for TLRs to generate
Zili Zhai et al.
Inflammation, 36(2), 346-354 (2012-10-12)
The nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) is commonly used to study free radicals. Due to its free radical trapping properties, DMPO is thought to reduce free radial-mediated oxidative damage and other related cellular responses. The purpose of this study
Zili Zhai et al.
Free radical biology & medicine, 53(1), 172-181 (2012-05-15)
The free-radical-operated mechanism of death of activated macrophages at sites of inflammation is unclear, but it is important to define it in order to find targets to prevent further tissue dysfunction. A well-defined model of macrophage activation at sites of
商品
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
相关内容
Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门