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质量水平
检测方案
≥98% (HPLC)
形式
powder
mp
219 °C
应用
detection
SMILES字符串
N[C@@H](CC(=O)c1ccccc1N)C(O)=O
InChI
1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1
InChI key
YGPSJZOEDVAXAB-QMMMGPOBSA-N
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应用
L-犬尿氨酸可用作吲哚胺-2,3-双加氧酶分析标准。它还可用作从培养细胞和培养基中提取和定量犬尿氨酸的标准。
生化/生理作用
L-犬尿氨酸是-L-色氨酸降解的关键中介物，通过犬尿氨酸途径形成烟酰胺腺嘌呤二核苷酸 (NAD+) 。它参与多种神经系统过程和疾病。L-犬尿氨酸是犬尿氨酸酶/犬尿氨酸水解酶底物；犬尿氨酸3-单加氧酶和犬尿氨酸-酮戊二酸转氨酶。
色氨酸降解途径的关键中间物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Evaluation of radiofluorinated carboximidamides as potential IDO-targeted PET tracers for cancer imaging
Xuan Huang
Oncotarget, 8(29), 46900-46914 (2017)
Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research (2012)
The Involvement of Neuroinflammation and Kynurenine Pathway in Parkinson's Disease
Anna Zinger
Parkinson's Disease (2011)
Kynurenine Pathway Metabolites in Humans: Disease and Healthy States
Yiquan Chen
International Journal of Tryptophan Research : IJTR, 2, 1-19 (2009)
Linnéa Asp et al.
Journal of inflammation (London, England), 8, 25-25 (2011-10-11)
The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites. Altered levels of KP-metabolites have been observed in neuropsychiatric and neurodegenerative disorders as well as in patients with
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