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Merck
CN

K2894

Sigma-Aldrich

PKAcβ, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

cAPKb

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

重组

expressed in baculovirus infected Sf9 cells

质量水平

产品线

PRECISIO® Kinase

检测方案

≥70% (SDS-PAGE)

形式

buffered aqueous glycerol solution

比活

423-573 nmol/min·mg

分子量

~65 kDa

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... PRKACB(5567)

生化/生理作用

PRKACB (protein kinase cAMP-activated catalytic subunit β) is a catalytic subunit allele of PKA (protein kinase A). Mutation in it is associated with neural tube defects. PRKACB can phosphorylate p65 in presence of cyclic adenosine monophosphate (cAMP).

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Seiko Susuki-Miyata et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(14), E1800-E1809 (2015-04-02)
Phosphodiesterase 4B (PDE4B) plays a key role in regulating inflammation. Roflumilast, a phosphodiesterase (PDE)4-selective inhibitor, has recently been approved for treating severe chronic obstructive pulmonary disease (COPD) patients with exacerbation. However, there is also clinical evidence suggesting the development of
J Simard et al.
Human genetics, 88(6), 653-657 (1992-03-01)
A cDNA for the human catalytic subunit (C beta) of cAMP-dependent protein kinase (PKA) has been cloned from a testis cDNA library. In the present study, we have determined the chromosomal localization of this gene using a cDNA for C
Jian Wu et al.
International journal of clinical and experimental pathology, 6(12), 2968-2974 (2013-12-03)
This study aimed to investigate the single nucleotide polymorphisms (SNPs) of PKA and neural tube defects (NTDs) in Chinese population. A total of 183 NTDs cases and 200 healthy controls were used in this study. 7 selected single nucleotide polymorphism

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