重组
expressed in baculovirus infected Sf9 cells
质量水平
产品线
PRECISIO® Kinase
检测方案
≥70% (SDS-PAGE)
形式
buffered aqueous glycerol solution
比活
423-573 nmol/min·mg
分子量
~65 kDa
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... PRKACB(5567)
生化/生理作用
PRKACB (protein kinase cAMP-activated catalytic subunit β) is a catalytic subunit allele of PKA (protein kinase A). Mutation in it is associated with neural tube defects. PRKACB can phosphorylate p65 in presence of cyclic adenosine monophosphate (cAMP).
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Proceedings of the National Academy of Sciences of the United States of America, 112(14), E1800-E1809 (2015-04-02)
Phosphodiesterase 4B (PDE4B) plays a key role in regulating inflammation. Roflumilast, a phosphodiesterase (PDE)4-selective inhibitor, has recently been approved for treating severe chronic obstructive pulmonary disease (COPD) patients with exacerbation. However, there is also clinical evidence suggesting the development of
Human genetics, 88(6), 653-657 (1992-03-01)
A cDNA for the human catalytic subunit (C beta) of cAMP-dependent protein kinase (PKA) has been cloned from a testis cDNA library. In the present study, we have determined the chromosomal localization of this gene using a cDNA for C
International journal of clinical and experimental pathology, 6(12), 2968-2974 (2013-12-03)
This study aimed to investigate the single nucleotide polymorphisms (SNPs) of PKA and neural tube defects (NTDs) in Chinese population. A total of 183 NTDs cases and 200 healthy controls were used in this study. 7 selected single nucleotide polymorphism
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