PRKACB
protein kinase, cAMP-dependent, catalytic, beta
别名:
PKACB
物种:
Human PRKACB (5567), Mouse Prkacb (18749), Rat Prkacb (293508), dog PRKACB (479975), chicken PRKACB (424542), naked mole-rat Prkacb (101721558), cow PRKACB (282323), domestic cat PRKACB (101095353), sheep PRKACB (101108785), Zebrafish prkacb (100538234)
UniProtKB ID:
基因ID:
- Human(5567) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011]
- Mouse(18749) protein kinase, cAMP dependent, catalytic, beta
- Rat(293508) protein kinase, cAMP dependent, catalytic, beta
- dog(479975) protein kinase, cAMP-dependent, catalytic, beta
- chicken(424542) protein kinase, cAMP-dependent, catalytic, beta
- naked mole-rat(101721558) protein kinase, cAMP-dependent, catalytic, beta
- cow(282323) protein kinase, cAMP-dependent, catalytic, beta
- domestic cat(101095353) protein kinase, cAMP-dependent, catalytic, beta
- sheep(101108785) protein kinase, cAMP-dependent, catalytic, beta
- Zebrafish(100538234) protein kinase, cAMP-dependent, catalytic, beta
- domestic guinea pig(100712694) protein kinase, cAMP-dependent, catalytic, beta
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Antibodies
货号
说明
物种反应性
应用
Anti-PRKACB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-PRKACB antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Monoclonal Anti-PRKACB antibody produced in mouse, clone 2G8-1D12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
抗-磷酸化-PKA CAT (pThr197) 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
Protein Kinase A Catalytic Subunit β, Active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
PKAcβ, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human