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生物来源
Tinospora sagittata
方案
≥95% (HPLC)
储存温度
2-8°C
InChI
1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1
InChI key
MXTLAHSTUOXGQF-UHFFFAOYSA-O
生化/生理作用
Phytochemical alkaloid found in medicinal plants. Anti-inflammatory. Potential therapeutic for gastrointestinal disorders.
Fengqing Liu et al.
Journal of pharmaceutical and biomedical analysis, 56(5), 1006-1015 (2011-09-06)
Incurred rabbit plasmas samples were utilized for method quality assessment in this study, where an optimized protein precipitation method for the preparation of rabbit plasma samples and a rapid and sensitive liquid chromatography-electrospray ionization-mass spectrometry for the simultaneous determination of
Beibei Zhang et al.
The Journal of pharmacy and pharmacology, 64(3), 413-419 (2012-02-09)
Postoperative ileus is major cause of postoperative complication and prolonged hospitalization. Jatrorrhizine, which is a protoberberine alkaloid isolated from the medicinal plants Berberis aristata and Coptis chinensis, has been found to increase contractility of gastric antral and ileum smooth muscles
Hua-dong Zhu et al.
Journal of chromatography. A, 1218(34), 5867-5871 (2011-07-26)
This paper for the first time describes the development of micelle to solvent stacking (MSS) to nonaqueous capillary electrophoresis (NACE). In this proposed MSS-NACE, sodium dodecyl sulfate (SDS) micelles transport, release, and focus analytes from the sample solution to the
Xinfeng Zhang et al.
Xenobiotica; the fate of foreign compounds in biological systems, 41(4), 290-296 (2011-02-16)
The absorption and transport mechanisms of berberine, palmatine, jateorhizine, and coptisine were studied using a Caco-2 cells uptake and transport model, with the addition of cyclosporin A and verapamil as P-glycoprotein (P-gp) inhibitors and MK-571 as a multidrug resistance-associated protein
Yan-Qiu Liu et al.
Journal of ethnopharmacology, 129(1), 121-126 (2010-03-10)
To investigate the effect of water extract of Rhizoma coptidis (WEC) and berberine on the activation of murine microglia N9 cells and corresponding mechanism related to mitochondria. Phagocytic activity of murine microglia N9 cells was measured by neutral red staining
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