产品名称
Anti-Human IgG (γ-chain specific) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
secondary antibodies
clone
polyclonal
form
buffered aqueous solution
technique(s)
immunoelectrophoresis: suitable
indirect ELISA: 1:50,000
quantitative precipitin assay: 2.0-3.0 mg/mL
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
Anti-Human IgG (γ-chain specific) antibody produced in rabbit has been used in western blotting.
Anti-Human IgG (γ-chain specific) antibody produced in rabbit was conjugated with BSA and coated over a nanofibrillar cellulose film to develop a platform for immunoassays and diagnostics.
Biochem/physiol Actions
IgG (immunoglobulin G) antibody participates in complement fixation and opsonization.
IgG antibody subtype provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
IgG (immunoglobulin G) antibody subtype is a predominant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. IgG is found in four subclasses IgG1, IgG2, IgG3 and IgG4. IgG has a monomeric structure.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Comparison of antibody molecules produced from two cell lines with contrasting productivities and aggregate contents
Ishii Y, et al.
Biological & Pharmaceutical Bulletin, b14-00729 (2014)
Protein disulfide isomerase does not control recombinant IgG4 productivity in mammalian cell lines
Hayes NVL, et al.
Biotechnology and Bioengineering, 105(4), 770-779 (2010)
Tanya J Knight et al.
Biotechnology and bioengineering, 119(12), 3408-3420 (2022-09-10)
Mammalian cells, particularly Chinese hamster ovary cells, are the dominant system for the production of protein-based biotherapeutics, however, product degradation, particularly of Fc-fusion proteins, is sometimes observed that impacts the quality of the protein generated. Here, we identify the site
James D Budge et al.
Data in brief, 29, 105217-105217 (2020-02-20)
The data presented in this article relates to the manuscript entitled 'Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production', published in the Journal Metabolic Engineering [1]. In the article
Hannes Orelma et al.
Biointerphases, 7(1-4), 61-61 (2012-10-12)
We introduce a new method to modify films of nanofibrillated cellulose (NFC) to produce non-porous, water-resistant substrates for diagnostics. First, water resistant NFC films were prepared from mechanically disintegrated NFC hydrogel, and then their surfaces were carboxylated via TEMPO-mediated oxidation.
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Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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