一般描述
免疫球蛋白G(IgG)属于免疫球蛋白家族,是一种广泛表达的血清抗体。免疫球蛋白由两条重链和两条轻链通过二硫键连接而成。它是一种糖蛋白。IgG通常是单体。IgG可进一步细分为四类,即IgG1、IgG2、IgG3和IgG4。大约70%的总免疫球蛋白由IgG组成。
特异性
观察到与纯化人IgA、IgM、Bence Jones Kappa和Bence Jones Lambda骨髓瘤蛋白的反应性。未观察到人IgG的Fc片段的反应性。
应用
山羊抗人IgG(Fab特异性)抗体可用于免疫测定。它也已在纤维素底物中用作固定化抗hIgG,以检测液体基质中的人免疫球蛋白G(hIgG)。
山羊抗人IgG(Fab特异性)抗体可用于捕获ELISA(1:10,000稀释)。
生化/生理作用
IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌,存在于血液和细胞外液中,可防止细菌、真菌和病毒引起的感染。母体IgG可通过胎盘转移至胎儿,胎盘对新生儿免疫防御感染至关重要。
外形
以含有15mM 叠氮化钠防腐剂的液体的供应
制备说明
脱脂
储存及稳定性
如需连续使用,可在2-8℃保存至多一月。对于更长期的存储,可对溶液进行等分并冷冻保存。不建议反复冻融。不建议储存在无霜冰箱中。如果长期储存时出现轻微浑浊,请在使用前通过离心澄清溶液。
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除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
常规特殊物品
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