产品名称
抗- 人 IgE(ε-特定链) 山羊抗, affinity isolated antibody, lyophilized powder
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
Ouchterlony double diffusion: suitable
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
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Application
抗人 IgE(ε 链特异性)抗体可用作各种免疫测定中的对照。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
IgE是一类只能由哺乳动物生产的免疫球蛋白。IgE 是由肥大细胞出于对过敏原的响应而分泌,对于针对寄生虫的免疫十分重要。它也是过敏反应或一型高血压的病理生理学中最重要的因子。当与纯化人IgA、IgG、IgM、本周氏κ和本周氏κ蛋白共同测试时,该产品只和人IgE反应。通过免疫电泳鉴定免疫球蛋白及其纯度。
Immunogen
纯化的人 IgE(骨髓瘤)
Physical form
冻干品,来自 0.01 mM 磷酸钠,0.015 mM 氯化钠,pH 7.2。
Preparation Note
用 0.135 M 氯化钠重构,得到 1 mg/mL 的抗体溶液。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Srinivasa Reddy Bonam et al.
Cells, 11(5) (2022-03-11)
Programmed death-ligand 1 (PD-L1) plays a key role in maintaining immune tolerance and also in immune evasion of cancers and pathogens. Though the identity of stimuli that induce PD-L1 in various human innate cells and their function are relatively well
Bettina Wedi et al.
Allergy, 75(9), 2229-2242 (2020-02-01)
Mas-related G protein-coupled receptor X2 (MRGPRX2) is regarded as a mast cell-specific receptor mediating non-IgE-dependent activation. We aimed to investigate whether human basophils and eosinophils express functional MRGPRX2. Flow cytometry, immunocytochemistry, immunofluorescence, Western blot, and RT-PCR were performed in highly
Shiteng Duan et al.
The Journal of clinical investigation, 129(3), 1387-1401 (2019-01-16)
Allergen immunotherapy for patients with allergies begins with weekly escalating doses of allergen under medical supervision to monitor and treat IgE mast cell-mediated anaphylaxis. There is currently no treatment to safely desensitize mast cells to enable robust allergen immunotherapy with
Stephen J Galli et al.
Nature medicine, 18(5), 693-704 (2012-05-09)
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to think of them in other contexts. However, a large body of evidence
Jie Zhao et al.
mAbs, 11(5), 837-847 (2019-04-06)
Asthma is characterized by airway hyperresponsiveness and inflammation, as well as underlying structural changes to the airways. Interleukin-4 (IL-4) is a key T-helper type 2 (Th2) cytokine that plays important roles in the pathogenesis of atopic and eosinophilic asthma. We
相关内容
抗体的质量决定了整个免疫检测的成败, 是在选择抗体时首选的考虑因素。基于Sigma®、Chemicon®、Upstate®、Mil l ipore®、 Calbiochem®和Novagen®等子品牌的强强联合,默克在创新的 免疫原设计、免疫、挑选、筛选和验证等方面有着数十年的经验, 创造出许多被广泛使用的抗体,如4G10,Neun,组蛋白修饰等抗 体都是相关领域的“金标”抗体。 我们的技术和科研背景使默克成为高质量抗体的主要设计者和生产 者,而不仅仅是经销商。毋庸置疑,我们的每个小瓶中的抗体都包 含着大量的科学研究成果。
Instructions
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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