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Merck
CN

I6284

Sigma-Aldrich

抗- 人 IgE(ε-特定链) 山羊抗

affinity isolated antibody, lyophilized powder

别名:

Anti Human Ige, Anti-Human IgE - Anti-Human IgE (ε-chain specific) antibody produced in goat, Anti-Human Ige

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

secondary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

human

技术

Ouchterlony double diffusion: suitable

储存温度

2-8°C

靶向翻译后修饰

unmodified

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一般描述

IgE是一类只能由哺乳动物生产的免疫球蛋白。IgE 是由肥大细胞出于对过敏原的响应而分泌,对于针对寄生虫的免疫十分重要。它也是过敏反应或一型高血压的病理生理学中最重要的因子。当与纯化人IgA、IgG、IgM、本周氏κ和本周氏κ蛋白共同测试时,该产品只和人IgE反应。通过免疫电泳鉴定免疫球蛋白及其纯度。

免疫原

纯化的人 IgE(骨髓瘤)

应用

抗人 IgE(ε 链特异性)抗体可用作各种免疫测定中的对照。

外形

冻干品,来自 0.01 mM 磷酸钠,0.015 mM 氯化钠,pH 7.2。

重悬

用 0.135 M 氯化钠重构,得到 1 mg/mL 的抗体溶液。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

Srinivasa Reddy Bonam et al.
Cells, 11(5) (2022-03-11)
Programmed death-ligand 1 (PD-L1) plays a key role in maintaining immune tolerance and also in immune evasion of cancers and pathogens. Though the identity of stimuli that induce PD-L1 in various human innate cells and their function are relatively well
Shiteng Duan et al.
The Journal of clinical investigation, 129(3), 1387-1401 (2019-01-16)
Allergen immunotherapy for patients with allergies begins with weekly escalating doses of allergen under medical supervision to monitor and treat IgE mast cell-mediated anaphylaxis. There is currently no treatment to safely desensitize mast cells to enable robust allergen immunotherapy with
Bettina Wedi et al.
Allergy, 75(9), 2229-2242 (2020-02-01)
Mas-related G protein-coupled receptor X2 (MRGPRX2) is regarded as a mast cell-specific receptor mediating non-IgE-dependent activation. We aimed to investigate whether human basophils and eosinophils express functional MRGPRX2. Flow cytometry, immunocytochemistry, immunofluorescence, Western blot, and RT-PCR were performed in highly
Stephen J Galli et al.
Nature medicine, 18(5), 693-704 (2012-05-09)
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to think of them in other contexts. However, a large body of evidence
Jie Zhao et al.
mAbs, 11(5), 837-847 (2019-04-06)
Asthma is characterized by airway hyperresponsiveness and inflammation, as well as underlying structural changes to the airways. Interleukin-4 (IL-4) is a key T-helper type 2 (Th2) cytokine that plays important roles in the pathogenesis of atopic and eosinophilic asthma. We

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