biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
Ouchterlony double diffusion: suitable
storage temp.
2-8°C
target post-translational modification
unmodified
General description
IgE是一类只能由哺乳动物生产的免疫球蛋白。IgE 是由肥大细胞出于对过敏原的响应而分泌,对于针对寄生虫的免疫十分重要。它也是过敏反应或一型高血压的病理生理学中最重要的因子。当与纯化人IgA、IgG、IgM、本周氏κ和本周氏κ蛋白共同测试时,该产品只和人IgE反应。通过免疫电泳鉴定免疫球蛋白及其纯度。
Immunogen
纯化的人 IgE(骨髓瘤)
Application
抗人 IgE(ε 链特异性)抗体可用作各种免疫测定中的对照。
Physical form
冻干品,来自 0.01 mM 磷酸钠,0.015 mM 氯化钠,pH 7.2。
Preparation Note
用 0.135 M 氯化钠重构,得到 1 mg/mL 的抗体溶液。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
相关内容
抗体的质量决定了整个免疫检测的成败, 是在选择抗体时首选的考虑因素。基于Sigma®、Chemicon®、Upstate®、Mil l ipore®、 Calbiochem®和Novagen®等子品牌的强强联合,默克在创新的 免疫原设计、免疫、挑选、筛选和验证等方面有着数十年的经验, 创造出许多被广泛使用的抗体,如4G10,Neun,组蛋白修饰等抗 体都是相关领域的“金标”抗体。 我们的技术和科研背景使默克成为高质量抗体的主要设计者和生产 者,而不仅仅是经销商。毋庸置疑,我们的每个小瓶中的抗体都包 含着大量的科学研究成果。
Instructions
Shiteng Duan et al.
The Journal of clinical investigation, 129(3), 1387-1401 (2019-01-16)
Allergen immunotherapy for patients with allergies begins with weekly escalating doses of allergen under medical supervision to monitor and treat IgE mast cell-mediated anaphylaxis. There is currently no treatment to safely desensitize mast cells to enable robust allergen immunotherapy with
Srinivasa Reddy Bonam et al.
Cells, 11(5) (2022-03-11)
Programmed death-ligand 1 (PD-L1) plays a key role in maintaining immune tolerance and also in immune evasion of cancers and pathogens. Though the identity of stimuli that induce PD-L1 in various human innate cells and their function are relatively well
Bettina Wedi et al.
Allergy, 75(9), 2229-2242 (2020-02-01)
Mas-related G protein-coupled receptor X2 (MRGPRX2) is regarded as a mast cell-specific receptor mediating non-IgE-dependent activation. We aimed to investigate whether human basophils and eosinophils express functional MRGPRX2. Flow cytometry, immunocytochemistry, immunofluorescence, Western blot, and RT-PCR were performed in highly
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I6284-1MG | 04061826703373 |