推荐产品
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
secondary antibodies
克隆
HP-6014, monoclonal
包含
15 mM sodium azide
技术
indirect ELISA: 1:5,000
同位素/亚型
IgG1
运输
dry ice
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此商品 | 54790U | 54775 | 54784 |
|---|---|---|---|
| particle size 5 μm | particle size 5 μm | particle size 5 μm | particle size 5 μm |
| separation technique hydrophilic interaction (HILIC), normal phase | separation technique hydrophilic interaction (HILIC), normal phase | separation technique reversed phase | separation technique anion exchange, hydrophilic interaction (HILIC), normal phase |
| matrix active group silica phase | matrix active group silica phase | matrix active group C18 (octadecyl) phase | matrix active group amino phase |
| matrix silica gel | matrix silica, fully porous particle | matrix octadecyl, silica particle platform | matrix amino |
| pore size 60 Å | pore size 60 Å | pore size 100 Å | pore size 100 Å |
| technique(s) HPLC: suitable | technique(s) HPLC: suitable | technique(s) HPLC: suitable | technique(s) HPLC: suitable |
一般描述
单克隆抗-人IgG2（小鼠 IgG1亚型）来源于小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生的杂交瘤。人IgG由四个亚类组成。
特异性
该抗体对人 IgG2 具有特异性，与其他 IgG 亚类不反应。该克隆已被 IUIS/WHO 研究挑选出为应用最广泛的 IgG2 特异性单克隆抗体。
应用
抗人IgG2单克隆抗体可用于酶联免疫吸附试验（ELISA）和蛋白质印迹。
也可用于
也可用于
- 印迹免疫固定法
- 免疫荧光法
- 血凝法
- 血凝抑制法
- 颗粒计数免疫分析法
- 细胞质IgG检测
生化/生理作用
抗多糖反应的主要是IgG2亚类，而蛋白质抗原产生的则是IgG1和IgG3抗体。脂多糖刺激外周血白细胞（PBL′s）中的IgG2反应。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Z Lazarova et al.
The Journal of investigative dermatology, 114(1), 178-184 (2000-01-05)
Patients with one form of cicatricial pemphigoid have IgG antibasement membrane autoantibodies against laminin 5 (alpha3beta3gamma2). Although passive transfer of rabbit anti-laminin 5 IgG to neonatal mice has been shown to induce subepidermal blisters that mimic those in patients, it
Identification of immune biomarkers related to disease progression and treatment efficacy in human visceral leishmaniasis
Portela A S B, et al.
Immunobiology, 223(3), 303-309 (2018)
A conserved Leishmania hypothetical protein evaluated for the serodiagnosis of canine and human visceral and tegumentary leishmaniasis, as well as a serological marker for the posttreatment patient follow-up
Ribeiro P A, et al.
Diagnostic Microbiology and Infectious Disease, 92(3), 196-203 (2018)
Negative immunodiffusion test results obtained with sera of paracoccidioidomycosis patients may be related to low-avidity immunoglobulin G2 antibodies directed against carbohydrate epitopes
Neves AR, et al.
Clinical and Diagnostic Laboratory Immunology, 10(5), 802-807 (2003)
D Thiagarajan et al.
ACR open rheumatology, 2(6), 344-356 (2020-05-12)
Immunoglobulin M antibodies against phosphorylcholine (anti-PCs) may be protective in atherosclerosis, cardiovascular disease (CVD), and systemic lupus erythematosus (SLE). We study immunoglobulin G1 (IgG1) and immunoglobulin G2 (IgG2) anti-PCs, with a focus on atherosclerosis and SLE. We determined anti-PCs by
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