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一般描述
人IgG是糖蛋白抗体，含有两条相等的轻链和一对相同的重链。 IgG具有四种不同亚型，范围从IgG1到IgG4。这些抗体可调节机体对过敏和病原性感染的免疫反应。IgG还与补体结合和自身免疫疾病有关。通过免疫电泳对正常人血清和 IgG 进行测试时，抗人 IgG（全分子）抗体对人 IgG 具有特异性。该抗体还与轻链反应。免疫球蛋白G（IgG）属于免疫球蛋白家族，是一种广泛表达的血清抗体。它由γ恒定 (C) 区的重链组成。该抗体的一级结构包含连接两条重链、重链和轻链，并位于链内的二硫键。
免疫原
人 IgG
外形
溶于0.01M磷酸盐缓冲盐水，pH 7.4，含有15 mM叠氮化钠作为防腐剂
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Tuerhongjiang Tuxun et al.
Scientific reports, 8(1), 4417-4417 (2018-03-15)
Fluorodeoxyglucose (FDG) uptake by alveolar echinococcosis (AE) liver lesions is a signal of their metabolic activity and of disease progression. In order to find a surrogate marker for this status, we investigated whether parameters of the peripheral and/or periparasitic immune
Laura E M Dunn et al.
Journal of virology, 97(2), e0189422-e0189422 (2023-02-07)
The ability of Epstein-Barr virus (EBV) to switch between latent and lytic infection is key to its long-term persistence, yet the molecular mechanisms behind this switch remain unclear. To investigate transcriptional events during the latent-to-lytic switch, we utilized Precision nuclear
Lorenzo Russo et al.
Nanoscale, 11(22), 10819-10827 (2019-05-29)
Myxovirus protein A (MxA) is a biomarker that can be used to distinguish between viral and bacterial infections. While MxA lateral flow assays (LFAs) have been successfully used for viral vs. bacterial differential diagnosis for children, the clinically relevant level
Xiaoran Wu et al.
Protein & cell, 4(11), 863-871 (2013-11-12)
Graft-versus-host disease (GVHD) is a prevalent and potential complication of hematopoietic stem cell transplantation. An animal model, xenogeneic GVHD (X-GVHD), that mimics accurately the clinical presentation of GVHD would provide a tool for investigating the mechanism involved in disease pathogenesis.
Algirdas Grevys et al.
iScience, 25(2), 103746-103746 (2022-02-05)
Monoclonal IgG antibodies are the fastest growing class of biologics, but large differences exist in their plasma half-life in humans. Thus, to design IgG antibodies with favorable pharmacokinetics, it is crucial to identify the determinants of such differences. Here, we
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